DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and srms

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001129722.2	Gene:	srms / 100192213	ZFINID:	ZDB-GENE-081022-95	Length:	492	Species:	Danio rerio

Alignment Length:	180	Identity:	62/180 - (34%)
Similarity:	95/180 - (52%)	Gaps:	25/180 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDG--KEGLIPSNYI-----EMKNHDWYY 62
            |..||.|.:::|||.::...|.::....| ..:..:|.|  :.||||:||:     |..|:.|||
Zfish    55 ALFDFVARSEEELSVKEGDKLSVIEKRGD-YVFAKKLTGSLESGLIPANYVALLKDEFANYKWYY 118

  Fly    63 GRITRADAEKLL--SNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFL-WVVKF 124
            |.|.|..|||||  |....|:||:|||||...::::|.:..:.|.||::.|.....:|: ..:.|
Zfish   119 GNINRQKAEKLLLSSENKTGSFLVRISESHSDEYTISARSENSVFHFRIHRSPIGAYFVSEKISF 183

  Fly   125 NSLNELVEYHRTASVSRS--------QDVKLRDMIP------EEMLVQAL 160
            .:|:||:.|::..|.|..        |..:|.||.|      |.|||:.|
Zfish   184 GTLDELIRYYQQNSRSLGCHIDQPCVQRRELFDMEPWERPREEFMLVKKL 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	16/49 (33%)
		SH2_Grb2_like	56..149	CDD:199828	36/103 (35%)
		SH3_GRB2_like_C	156..208	CDD:212739	3/5 (60%)
srms	NP_001129722.2	SH3	52..106	CDD:302595	17/51 (33%)
		SH2	114..197	CDD:214585	31/82 (38%)
		PKc_like	220..481	CDD:304357	5/14 (36%)
		STYKc	229..478	CDD:214568	3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910