DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbc and Cept1

DIOPT Version :9

Sequence 1:	NP_001246300.1	Gene:	bbc / 36496	FlyBaseID:	FBgn0033844	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001280623.1	Gene:	Cept1 / 99712	MGIID:	2139793	Length:	416	Species:	Mus musculus

Alignment Length:	374	Identity:	200/374 - (53%)
Similarity:	256/374 - (68%)	Gaps:	4/374 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LSAQQLRKLSEHKYSCFSVSLLDPLLQPWWNWLVAQTPLWLAPNLITIVGLILNVVTTLILICYS 76
            ||..||::|.||:|.....|||:||:|.:|.|||.:.|.|:|||||||:||.:|:.||::|:.|.
Mouse    43 LSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYC 107

  Fly    77 PNGVEAPPRWTCLLCALGLFIYQSLDSIDGKQARRTNTSSPLGELFDHGCDSISTVFVALSACIS 141
            |...|..|.|..:.||.|||||||||:||||||||||:||||||||||||||:|||||.|..||:
Mouse   108 PTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIA 172

  Fly   142 CQLGHYPNWLFFQCFCAIALFYCAHWQTYVSGTMRFGRIDVTEAQFSIIAIHLVSAALGPEIWLT 206
            .|||..|:|:||.||....:|||||||||||||:|||..||||:|..||...|:|..:||..|..
Mouse   173 VQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIFDVTESQILIILFQLLSGTVGPWFWNF 237

  Fly   207 KLPHFNCESRFLPIYVACGVDLILALRYTKCILTEGCGKNGSSVAGTSVLSPSIPLTLVVLPALM 271
            .:|..|.:.:.||........:.....|.:.|.|.|.|||||::||||||||.:.:..|:..|:|
Mouse   238 TIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVM 302

  Fly   272 IAQKSPQNLFTEHASVYIMAFGMVAAKVTNKLVIAHMTKAEMEYLDWSLLGPSLLFLNQYFNCIV 336
            |.:||...||.:|..:||:.||.|:||:|||||:|||||:||...|.:.:||:||||:||||..:
Mouse   303 IYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFI 367

  Fly   337 PEIWLLWFTLIWGTQDLLRYCAQVCLEICQHLRIDLFRIPYTPKGATPH 385
            .|..:||..||:...||:|||..||.:|..||.|.:|||    |.:|.|
Mouse   368 DEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRI----KASTAH 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbc	NP_001246300.1	CDP-OH_P_transf	12..328	CDD:294308	172/315 (55%)
Cept1	NP_001280623.1	CDP-OH_P_transf	43..407	CDD:294308	197/367 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836375
Domainoid	1	1.000	264	1.000	Domainoid score	I1905
eggNOG	1	0.900	-	-		E1_COG5050
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	423	1.000	Inparanoid score	I1755
Isobase	1	0.950	-	0	Normalized mean entropy	S1754
OMA	1	1.010	-	-		QHG53654
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002101
OrthoInspector	1	1.000	-	-		otm42913
orthoMCL	1	0.900	-	-		OOG6_100740
Panther	1	1.100	-	-	O	PTHR10414
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1820
SonicParanoid	1	1.000	-	-		X1064
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.740