DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bbc and cept1b

DIOPT Version :9

Sequence 1:	NP_001246300.1	Gene:	bbc / 36496	FlyBaseID:	FBgn0033844	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001103187.1	Gene:	cept1b / 570720	ZFINID:	ZDB-GENE-071004-33	Length:	415	Species:	Danio rerio

Alignment Length:	373	Identity:	204/373 - (54%)
Similarity:	266/373 - (71%)	Gaps:	3/373 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ILSAQQLRKLSEHKYSCFSVSLLDPLLQPWWNWLVAQTPLWLAPNLITIVGLILNVVTTLILICY 75
            :||..||::|.||:||....|||:|::|.:|.|||.:.|.|:||||||||||:.|:.|||:|:.|
Zfish    42 VLSRHQLKRLEEHRYSSSGRSLLEPIMQQYWEWLVNRMPPWIAPNLITIVGLVTNIFTTLVLVYY 106

  Fly    76 SPNGVEAPPRWTCLLCALGLFIYQSLDSIDGKQARRTNTSSPLGELFDHGCDSISTVFVALSACI 140
            .|...|..|.|..||||:|||:|||||:||||||||||:||||||||||||||:|||||.|...|
Zfish   107 CPTATEQAPLWAYLLCAVGLFVYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTSI 171

  Fly   141 SCQLGHYPNWLFFQCFCAIALFYCAHWQTYVSGTMRFGRIDVTEAQFSIIAIHLVSAALGPEIWL 205
            :.|||.:|:|:||.||..:.:|||||||||||||:|||.|||||.|..||.::|::|..|...|.
Zfish   172 AVQLGTHPDWMFFCCFAGMFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIILVYLLAAVGGSAFWQ 236

  Fly   206 TKLPHFNCESRFLP-IYVACGVDLILALRYTKCILTEGCGKNGSSVAGTSVLSPSIPLTLVVLPA 269
            :.:|..|.:.:.:| :....|| :.....|.:.|.|.|.|||||::||||||||.:.:..|::.|
Zfish   237 SPIPVINIQMKIIPALCTFIGV-VFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPVLHIGSVIILA 300

  Fly   270 LMIAQKSPQNLFTEHASVYIMAFGMVAAKVTNKLVIAHMTKAEMEYLDWSLLGPSLLFLNQYFNC 334
            :||.:||...||.:|..:||:|||.|:||:|||||:|||||:||...|.:.|||.||||:||||.
Zfish   301 MMIYKKSAVQLFQKHPCLYILAFGFVSAKITNKLVVAHMTKSEMHLHDVAFLGPGLLFLDQYFNS 365

  Fly   335 IVPEIWLLWFTLIWGTQDLLRYCAQVCLEICQHLRIDLFRI-PYTPKG 381
            .:.|..:||.:||....||:|||..||.||..||.|.:|:| |.:..|
Zfish   366 FIDEYLVLWISLILSLFDLVRYCVSVCNEIASHLHICVFKIKPQSAAG 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bbc	NP_001246300.1	CDP-OH_P_transf	12..328	CDD:294308	177/316 (56%)
cept1b	NP_001103187.1	CDP-OH_P_transf	43..381	CDD:294308	188/338 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579866
Domainoid	1	1.000	262	1.000	Domainoid score	I1903
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	427	1.000	Inparanoid score	I1721
OMA	1	1.010	-	-		QHG53654
OrthoDB	1	1.010	-	-		D399621at33208
OrthoFinder	1	1.000	-	-		FOG0002101
OrthoInspector	1	1.000	-	-		otm25262
orthoMCL	1	0.900	-	-		OOG6_100740
Panther	1	1.100	-	-	O	PTHR10414
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1820
SonicParanoid	1	1.000	-	-		X1064
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900