DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cid and H3-5

DIOPT Version :9

Sequence 1:	NP_523730.2	Gene:	cid / 36495	FlyBaseID:	FBgn0040477	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001013721.2	Gene:	H3-5 / 440093	HGNCID:	33164	Length:	135	Species:	Homo sapiens

Alignment Length:	179	Identity:	55/179 - (30%)
Similarity:	70/179 - (39%)	Gaps:	56/179 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 RRSSTLRRDAGRRQP-------AARDS--STSGEEEDQENRYPTTRSPQTRRMTVQQESKTRAAG 110
            |...|.|:..|.:.|       |||.|  ||.|.   :.:||                    ..|
Human     3 RTKQTARKSTGGKAPRKQLATKAARKSTPSTCGV---KPHRY--------------------RPG 44

  Fly   111 PVAAQNQTRRRKAANPMSRAKRMDREIRRLQHHPGTLIPKLPFSRLVREFIVKYSDDEPLRVTEG 175
            .||.                    |||||.|.....||.||||.|||||....::.|  ||....
Human    45 TVAL--------------------REIRRYQKSTELLIRKLPFQRLVREIAQDFNTD--LRFQSA 87

  Fly   176 ALLAMQESCEMYLTQRLADSYMLTKHRNRVTLEVRDMALMAYICDRGRQ 224
            |:.|:||:.|.||...|.|:.:...|..|||:..:|:.|...|  ||.:
Human    88 AVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRI--RGER 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cid	NP_523730.2	H4	135..219	CDD:419976	35/83 (42%)
H3-5	NP_001013721.2	PTZ00018	1..135	CDD:185400	55/179 (31%)
		Histone	1..131	CDD:278551	53/174 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41		12/40 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1745
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810