Protein Alignment cid and HFE

DIOPT Version :9

• Sequence 1: NP_523730.2
• Gene: cid / 36495
• FlyBaseID: FBgn0040477
• Length: 225
• Species: Drosophila melanogaster
• Sequence 2: NP_000401.1
• Gene: HFE / 3077
• HGNCID: 4886
• Length: 348
• Species: Homo sapiens
• Alignment Length: 81
• Identity: 21/81 - (25%)
• Similarity: 32/81 - (39%)
• Gaps: 17/81 - (20%)

  Fly    43 FTTSQLTLQDN---NRRSSTLRRDAGRRQPAARDSSTSG------EEEDQENRYPTT---RSPQT 95
            ||....|:.:|   ::.|.||:...|...  ..|:||.|      :.:|.....|.|   |:.:.
Human    98 FTVDFWTIMENHNHSKESHTLQVILGCEM--QEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEP 160

  Fly    96 RRMTVQQE---SKTRA 108
            |....:.|   .|.||
Human   161 RAWPTKLEWERHKIRA 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cid	NP_523730.2	H4	135..219	CDD:419976
HFE	NP_000401.1	Alpha-1	23..114		4/15 (27%)
		MHC_I	27..202	CDD:298647	21/81 (26%)
		Alpha-2	115..205		17/64 (27%)
		IgC_MHC_I_alpha3	206..298	CDD:143322
		Alpha-3	206..297
		Connecting peptide	298..306

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1745
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900