Protein Alignment cbs and ccdc186

DIOPT Version :9

• Sequence 1: NP_610875.1
• Gene: cbs / 36492
• FlyBaseID: FBgn0086757
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_009305037.1
• Gene: ccdc186 / 557112
• ZFINID: ZDB-GENE-100318-3
• Length: 955
• Species: Danio rerio
• Alignment Length: 622
• Identity: 134/622 - (21%)
• Similarity: 262/622 - (42%)
• Gaps: 124/622 - (19%)

  Fly    35 LRSRRVSINSNSADDVGGGGFYNESEQLCELRSQCNELTTK-LSTVTQGLQQ------LQEEKTR 92
            |::.:.:.|.|..|........:|.|:.....|..:||..: |::.::|:::      ||:
Zfish   180 LQNSQTNANLNPYDTECSRKLLSEIERSLSQESLLDELEDELLNSQSEGVRKGSHPNGLQK---- 240

  Fly    93 VDKTNEILLE---SVRVAQTQKDI--YCEEQEKIQNLQQ---IEIDKLKNLLSFREQESVDRMGL 149
             |:.:.:|.|   ..:.:|.:|.|  ..||.:|.|.|..   .|.|.:::.|..|
Zfish   241 -DQNSMVLFEKCVQYKYSQQEKAIKGLLEENKKHQELILGICSEKDNMRDELKKR---------- 294

  Fly   150 MRQQTQQIESLSEELERLRPIESVAEDLRDELEQLRHSTQQEKNLLTTTLAAVQEENRHLKKRM- 213
            |..:.|.:.::.:...|   :|.:.::|:|..::|.|..|..||       |:|:..|.:..|:
Zfish   295 METEKQHLYTIKKFESR---VEELTKELKDSRDKLVHQDQAAKN-------AIQQMQREMAYRLE 349

  Fly   214 ---KIVEESRLES----LGKLNSEQQVQALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALETQ 271
               |..||:|.|.    :..:..|::...|.||.:.||:.|.||..::.  |.:..|..||.|.
Zfish   350 QANKKCEEARQEKETMVMKYVRGEKEALDLRREKEQLEKKLREATAEVD--KQARRGNTLAQEK- 411

  Fly   272 VSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEKAKDEIKQRDDKVKLLEEEIDELSVALK 336
             .||.:....:..|..:.::              ||||.|:||.....|||..:.::...:.:.|
Zfish   412 -GRLQQLYDAKENEVTRLMR--------------ELEKVKEEINSHVIKVKWAQNKLKSETDSHK 461

  Fly   337 ECREENEQQVLFERNKSQNLETEVKDLKTRLTAADDRFSEYSSNAEQVAQKLRVQVTEKQEQLD- 400
            |.::                  .:|:...:||.|.:...:...|.:.:.:..:.....|..:||
Zfish   462 ETKD------------------RLKETTAKLTQAKEETEQIRKNCQDMIRTYQESEEIKSNELDA 508

  Fly   401 ---ETIMQLEIEREEKMTAI-LRNAEIAQSEDILR------QQLRLERSEASDLQERNNQLVRDI 455
               ||..:||.:::|:...: :..|:|.:.||:.|      .:|...|::...|::...:...::
Zfish   509 KLRETKGELEKQKQEQTDQLEMHKAKIKELEDLKRTFKEGMDELTTLRTKVKCLEDERPRWEDEL 573

  Fly   456 SEARQTLQQVSSTAQDNADKLT-------EFERVQLEIIEKNKTIKTLNQRLIDLKKTVQ----- 508
            .:.|:.:.:..:..|:..:|||       :.:|.:.||....:.::.||.::.||::.::
Zfish   574 CKYREIINRQKAEIQNQREKLTAITRLEEQHQRDEQEIASLQEEVENLNSQITDLQRDIEGSRTR 638

  Fly   509 --------KELRSAQISTDSESHPTTTPGHRISSSSLEAFS-TGDKGNCV--IMDEVNF--QYLK 560
                    ::|.|......|||:.......|::|||.|..: ..|...|:  :||.:..  |..:
Zfish   639 EAELLGFTEKLSSKNAQLQSESNSLQAQLDRLNSSSRELHNKLEDTERCLSDMMDRLKTEEQQRQ 703

  Fly   561 HVIVKFLTSR---EVEARHLVRAVSTLL-QLTTEEEK 593
            ..::...|.|   :.|...|...|..|. :|.|::.|
Zfish   704 EEVLALQTERTSLQTETSQLKTRVEELRDELVTQKRK 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cbs	NP_610875.1	AmyAc_family	<276..>372	CDD:298606	17/95 (18%)
		Grip	553..598	CDD:197860	10/47 (21%)
ccdc186	XP_009305037.1	SbcC	289..>764	CDD:223496	108/508 (21%)
		DUF342	<414..505	CDD:302792	20/122 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0992
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900