Protein Alignment cbs and GCC88

DIOPT Version :9

• Sequence 1: NP_610875.1
• Gene: cbs / 36492
• FlyBaseID: FBgn0086757
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_650055.1
• Gene: GCC88 / 41350
• FlyBaseID: FBgn0037881
• Length: 695
• Species: Drosophila melanogaster
• Alignment Length: 730
• Identity: 147/730 - (20%)
• Similarity: 283/730 - (38%)
• Gaps: 207/730 - (28%)

  Fly     8 KIKEETGDDVVQSANQRYPGNNNNNYR-LRSRRVSINSNSADDVGGGGFYNESEQLCELRSQCNE 71
            |.||.....:...|.....|.:.:..| |.|::.|  ::|||....|..........|     .:
  Fly    38 KEKEALETSLAAHAEATAVGESGSPARELESKKTS--TDSADGATEGAAPGPPAPPAE-----GQ 95

  Fly    72 LTTKLSTVTQGLQQLQEEKTRVDKTNEILLESVRVAQTQKDIYCEEQEKIQNLQQIEIDKLKNLL 136
            |.|::.|:...|..|..||:|::.:.:...:.:|....||:         |.:|  |::......
  Fly    96 LQTQIITLMNSLATLSAEKSRMEASFQADKKQLRSQIAQKE---------QTIQ--ELNTRAKEQ 149

  Fly   137 SFREQESVDRM---GLMRQQTQQIESLSEELERLRPIESVAEDLRDELEQLRHSTQQEKNLLTTT 198
            :.|.:..||.:   .::.:|.::.|: :.::..:|.::.:..|.|    .|:.:.:.:.|...|.
  Fly   150 AARAKSDVDEIKAKWIVERQEREKET-NNQMLMIRELQKLYADER----HLKDNIEMQLNNFKTQ 209

  Fly   199 LAAVQEENRHLKKRMKIVEESR---------LESLGKLNSEQQVQALIREHKLLEQHLEEAHLQL 254
            .|:.:.||..|::....::|:|         .|.....::.....||:::.:|..|.|:|.|.
  Fly   210 FASNEAENSRLRELQSQLKEARSQLKQFQAKTEHSAAASASADSAALLQQVRLEMQQLKEQHA-- 272

  Fly   255 SDIKGSWSGQNLALETQVSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEK---AKDEIKQ 316
                       :|:..:..|:.:  |||.:.::.||  .:|.:.|.:....||..   :.|.::|
  Fly   273 -----------VAIRQEQRRVLR--AEEQSRRQAAL--HEDRVASLEARLAELSTTVGSYDRLRQ 322

  Fly   317 RD-DKVKLLEEEIDELSVALKECREENEQQVLFERNKSQNLETEVKDLKTRLTAADDR------F 374
            :| |.:..|::::.:|..|  ..|..:..:.|.|......|..|:..||..||.|:.|      .
  Fly   323 QDQDSIHDLKQQLQDLEQA--HVRPTSNSRALNEDVDVATLVDEMVRLKKLLTTANARSANPLDL 385

  Fly   375 SEYSSNAEQVAQKLRVQVTEKQEQLDETIMQLEIEREEKMTAILRNAEIAQSEDILRQQLRLERS 439
            .|..|.:.|.|.::... ...::||......||..::::              .:|.|:::|:.|
  Fly   386 GEILSFSGQTATRVESH-AHCEQQLQGVQQMLEASKQQR--------------QLLEQKVQLQHS 435

  Fly   440 EASDLQERNNQLVRDISEARQTLQQVSSTAQDNADKL--------TEFERVQLEIIEKNKTIKTL 496
            ....|||:...|.|:|.||...|:|       ..:||        |:::..:.|:  :|:|...|
  Fly   436 HIQTLQEKVQVLNRNIDEAEVELKQ-------QGEKLRLALKNERTKWQEAKAEL--ENETRCKL 491

  Fly   497 NQRLIDLKKTVQKE-LRSAQISTDSES------------HPTTTPGHRISSSSLEA--------- 539
            |    :|::.:||: .||.|:..:.|.            |..:..|..:::.:|||
  Fly   492 N----ELEQLLQKQRQRSLQLLDEKEQEIKTLQTSFEVFHSASGVGSTLATPTLEAAADSFHYSS 552

  Fly   540 --------------------FSTGDKGNC--------------------------------VIMD 552
                                .|.|:  ||                                .|.|
  Fly   553 DTDSVEGEQRERKLKVRSKKMSMGE--NCHMLHYANELARKDIEITTLRKAKYAAESTLRKAIQD 615

  Fly   553 EV-----------------------------NFQYLKHVIVKFLTSREVEA-RHLVRAVSTLLQL 587
            :|                             |.:|||:||:.::.:|:.:. ||::.|:|.:||.
  Fly   616 KVTSQQEMHEKIECLKEQVDRLERCKTREGANLEYLKNVIISYIVTRDADGKRHMLNAISAVLQF 680

  Fly   588 TTEEEKLLHDTLNWK 602
            |..|.:.::.:...|
  Fly   681 TAAEMQAINASFQKK 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cbs	NP_610875.1	AmyAc_family	<276..>372	CDD:298606	26/99 (26%)
		Grip	553..598	CDD:197860	16/74 (22%)
GCC88	NP_650055.1	GRIP	646..688	CDD:279767	15/41 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23157
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030