Protein Alignment Golgin97 and golga1

DIOPT Version :10

• Sequence 1: NP_610875.1
• Gene: Golgin97 / 36492
• FlyBaseID: FBgn0086757
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_957132.2
• Gene: golga1 / 393811
• ZFINID: ZDB-GENE-040426-1237
• Length: 862
• Species: Danio rerio
• Alignment Length: 872
• Identity: 220/872 - (25%)
• Similarity: 358/872 - (41%)
• Gaps: 287/872 - (32%)

  Fly     1 MFATLKNKIKEETGDDVVQSANQRYPGNNNNNYRLRSRR--VSINSNSADDVGGGGFYNE---SE 60
            |||.||.|:.||.   .....:.|.|       |..|:.  .|:.::|.||....|..:.   |.
Zfish     1 MFAKLKKKLAEEA---ATAPRSGRIP-------RSMSKESITSVGADSGDDFASDGSSSRDDFSS 55

  Fly    61 QLCELRSQCNELTTKLSTVTQGLQQLQEEKTRVD---------------------KTNEI-LLES 103
            |:.....|..:|..|||...:.|:.:|:.|.:::                     :||.. :.|:
Zfish    56 QIQRRNDQIRKLEAKLSDYAEQLRLMQKTKEKLEIALEKYQDSSMRKLQDQNESFQTNRAKMAEA 120

  Fly   104 VRVAQTQKD------IYCEEQEK--------------------------IQNLQQIEIDKLKNLL 136
            :.:|..:||      :...||||                          ::..||.|:.|:|::|
Zfish   121 MSLALEKKDQEWMEKLASLEQEKLSLTSRLDEMTEQSLSLFQKRDDLDELEGFQQQELAKVKHML 185

  Fly   137 SFREQE---------------SVDRMGL---------------------MRQQTQQIESLSE--- 162
            ..||::               :..|:.|                     .:.|.|:.|.|||
Zfish   186 LRREEQLNQREKELKLRGEELNTARLTLGKTQDKLYELGEEHEEICRTNSQLQAQRDELLSEKEE 250

  Fly   163 -------------ELERLRPIESVAED-----------------LRDELEQLRHSTQQEKNLLTT 197
                         ||::|  |:.|:||                 |:.|..:|:...:|.||.:..
Zfish   251 AERRVVDLERREQELQQL--IQQVSEDFQKAQSNAEALEKSMEHLQSEHNKLKLQHEQHKNKVAV 313

  Fly   198 T-------LAAVQEENRHLKKRMKIVEESRLESLGKLNSEQQVQALIREHKLLEQHLEEAHLQLS 255
            |       |:.:||:...|::|::          ...:.::.:|.|::|...|||.||||..:|.
Zfish   314 TEEERERILSDLQEKAASLERRLE----------ANFSQDEHLQELLKEKSSLEQRLEEARGELL 368

  Fly   256 DIKGSWSGQNLALETQVSRLSKQVAEETTEKRKALKSRDDAIES-RKQVSFELEKAKDEIKQRDD 319
            ..|.|.:....:||.||||.:..:.:..|    .:|.:||:.:: |::...::...:..:....:
Zfish   369 QEKTSHTTAVSSLEAQVSRQNASIIDLQT----LVKHKDDSSKAYRERTDAQISDLEQRLADCAE 429

  Fly   320 KVKLLEEEI-------DELSVALKECREENEQQVLFER----NKSQNLETEV----KDLKTRLTA 369
            |:|.|::::       |:|.:...|.||..:|||..:|    .|:..||.|:    :|.:|....
Zfish   430 KMKSLQQQLKDSQMHTDKLQMEWSEERERLQQQVSTQRQRGLEKTARLEEELLAVQRDRETEANK 494

  Fly   370 ADDRF--------------SEYSSNAEQVAQKL---RVQVTEKQ-------EQLDETIMQLEIER 410
            ..|..              .|..|..|.:..:|   |.:::.:|       :.|:||..|.|..:
Zfish   495 YQDNLRLLEEEKNSLLRSKGETDSTVESLTAELEQSRAEMSSRQTVSVEIAKALEETRKQREELQ 559

  Fly   411 EE--KMTAILRNA--EIAQ-SEDI---------LRQQLRLERSEASDLQ---------------E 446
            ::  |||..|..|  |::: |:|:         |:::|:..||..|.||               |
Zfish   560 QQVSKMTESLVKAEQEVSRLSQDLGVKEEEVNALKEELQAARSSLSSLQAECESRRLEAEEKERE 624

  Fly   447 RNNQLVRDISEARQTLQQVSS---------------TAQDNADK-------------LTEFERV- 482
            .|:||.....|..:..||:||               ||..:||:             |.:.::|
Zfish   625 HNSQLTSLQQEVLRQTQQLSSYQSRVSDLESEVLSLTAHSHADECEGEQNGTVTVSDLDQLQKVN 689

  Fly   483 ---QLEIIEKNKTIKTLNQRLIDLKKTVQKEL--------------------RSAQISTDSESHP 524
               :.::.|||||||.|.|||.:||:|:||||                    |||:.:......|
Zfish   690 KDLEQQLAEKNKTIKQLQQRLAELKRTLQKELKLKPDPDSEMKERLQDGRQERSAEKTVLETPMP 754

  Fly   525 TTTPGHRISSSSLEAFSTGD---KGNCVIMD--EVNFQYLKHVIVKFLTSREVEARHLVRAVSTL 584
            |..|...:..|......|.:   ..:..|.|  |:||:|||||::||::|||.||..|:||||.|
Zfish   755 TAAPSPALGLSQTPGPITPNTTVTNSSDITDTREINFEYLKHVVLKFMSSREAEAFQLIRAVSVL 819

  Fly   585 LQLTTEEEKLLHDTLNWKMSWFGMKPT 611
            |..:.|||.:|..||.:||||||.||:
Zfish   820 LHFSKEEEDMLKQTLEYKMSWFGSKPS 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Golgin97	NP_610875.1	SMC_prok_B	<71..465	CDD:274008	127/592 (21%)
		Grip	553..598	CDD:197860	26/44 (59%)
golga1	NP_957132.2	GumC	<47..>244	CDD:442439	32/196 (16%)
		Smc	<160..>719	CDD:440809	133/574 (23%)
		Grip	788..833	CDD:197860	26/44 (59%)