DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cbs and Y45F10B.8

DIOPT Version :9

Sequence 1:	NP_610875.1	Gene:	cbs / 36492	FlyBaseID:	FBgn0086757	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_502615.1	Gene:	Y45F10B.8 / 189918	WormBaseID:	WBGene00012872	Length:	244	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	46/217 - (21%)
Similarity:	100/217 - (46%)	Gaps:	32/217 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 KRMKIVEESRLESLGKLNSEQQVQALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALETQVSRL 275
            |.:|.:|  ...|....|..|.:..|.||       ||: |:.:.:.|.....:||.|:..:...
Worm     2 KSLKFME--NFISTVPFNMWQNMAKLKRE-------LED-HIDMPEQKAEKFFENLQLDIMIMAA 56

  Fly   276 SKQVAEETTEKRKALKSRDDAIESRKQVSFELEKAK---DEIKQRDDKVKLLEEEIDELSVALKE 337
            .|.:|.:..:..|      .|:.:::.::..|:|..   |::::.::::|:|:|::|:|...:.:
Worm    57 EKDIATDEVDSVK------QALMNQQMITQHLKKRNEYLDDLEEANERIKILDEKLDKLEAKISK 115

  Fly   338 CREENEQQVLFERNKSQNLETEVKDLKTRLTAADDRFSEYSSNAEQVAQKLRVQVTEKQE----- 397
            ..|...|.|.....|.:.|:|..|::|    ..||..|.:    :|...:|:....|.::
Worm   116 TEESLVQSVSMLLEKDEQLKTIRKEMK----IMDDERSAF----DQELTRLKTSRLENEKSSLAS 172

  Fly   398 QLDETIMQLEIEREEKMTAILR 419
            :::.||..|..:.|.::..:::
Worm   173 RVECTICYLSYDNEARVPRVMK 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbs	NP_610875.1	AmyAc_family	<276..>372	CDD:298606	20/98 (20%)
cbs	NP_610875.1	Grip	553..598	CDD:197860
Y45F10B.8	NP_502615.1	Smc	20..>175	CDD:224117	37/176 (21%)
		RING_Ubox	175..221	CDD:388418	4/20 (20%)
		RING-HC finger (C3HC4-type)	176..220	CDD:319361	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000