DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cbs and T01C3.3

DIOPT Version :9

Sequence 1:	NP_610875.1	Gene:	cbs / 36492	FlyBaseID:	FBgn0086757	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_506687.2	Gene:	T01C3.3 / 179997	WormBaseID:	WBGene00011320	Length:	230	Species:	Caenorhabditis elegans

Alignment Length:	176	Identity:	38/176 - (21%)
Similarity:	73/176 - (41%)	Gaps:	52/176 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 ESLGKLNSEQQVQALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALETQVSRLSKQVAEETTEK 286
            |::.||.|      |....:::|..:::....|..:|.|   |.|::...:
Worm    17 EAIAKLTS------LFGMMRMMEAEIKDQRNNLQALKNS---QRLSVRGSI-------------- 58

  Fly   287 RKALKSRDDAIESRK--QVSFELEKAKDEIKQRDDKVK--------------LLEEEIDELSVAL 335
            :..:.||.|.|..|:  :...:|.|...|:|.:|:|:|              ||:||.::..|::
Worm    59 QSNMSSRTDGILQRRLDETERKLAKTSAELKAKDEKLKKETASLEASREAHRLLQEESNKSKVSV 123

  Fly   336 KECREENEQQVLFERNKSQNLETEVKD---LKTRLTAADDRFSEYS 378
                    .::.|:.|:..:  ..||:   ||.:|...:.|.:.||
Worm   124 --------MRLTFKLNRITH--ESVKEQAVLKKKLLDCETRLATYS 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbs	NP_610875.1	AmyAc_family	<276..>372	CDD:298606	24/114 (21%)
cbs	NP_610875.1	Grip	553..598	CDD:197860
T01C3.3	NP_506687.2	EnvC	<17..>122	CDD:227278	27/127 (21%)
		modified RING-HC finger (C3HC3D-type)	161..206	CDD:319361
		RING_Ubox	161..206	CDD:388418
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000