Protein Alignment cnn and Cdk5rap2

DIOPT Version :10

• Sequence 1: NP_001246293.1
• Gene: cnn / 36491
• FlyBaseID: FBgn0013765
• Length: 1378
• Species: Drosophila melanogaster
• Sequence 2: NP_666102.2
• Gene: Cdk5rap2 / 214444
• MGIID: 2384875
• Length: 1822
• Species: Mus musculus
• Alignment Length: 35
• Identity: 11/35 - (31%)
• Similarity: 18/35 - (51%)
• Gaps: 7/35 - (20%)

  Fly    61 VLKTLIKKPKKPNSANRKCVLVRLSTGKELVAYIP 95
            :|..:::|||.|:|..:|       .|:..|..||
Mouse  1090 ILLAVLRKPKGPHSRQKK-------PGQSNVGGIP 1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cnn	NP_001246293.1	Cnn_1N	101..170	CDD:462333
		Smc	<138..>404	CDD:440809
		SMC_prok_B	498..1200	CDD:274008
		Smc	<929..>1247	CDD:440809
Cdk5rap2	NP_666102.2	CM1 motif, interacts with the gTuRC. /evidence=ECO:0000250|UniProtKB:Q96SN8	50..93
		Interaction with NCKAP5L. /evidence=ECO:0000250|UniProtKB:Q96SN8	57..195
		Cnn_1N	60..128	CDD:462333
		SMC_N	137..>455	CDD:481474
		EnvC	373..>613	CDD:443969
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1022..1046
		Interaction with PCNT and AKAP9. /evidence=ECO:0000269|PubMed:20471352	1201..1822
		CCDC158	<1204..>1593	CDD:464943
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1350..1391
		SMC_prok_B	<1399..>1584	CDD:274008
		Required for centrosomal attachment, Golgi targeting and CALM1 interaction. /evidence=ECO:0000250	1655..1822
		Interaction with CDK5R1. /evidence=ECO:0000250	1655..1697
		Interaction with PCNT. /evidence=ECO:0000269|PubMed:20471352	1688..1822
		Required for centrosomal attachment, Golgi localization and CALM1 interaction. /evidence=ECO:0000250	1790..1799