Protein Alignment Ser8 and KLK4

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 75/241 - (31%)
• Similarity: 119/241 - (49%)
• Gaps: 19/241 - (7%)

  Fly    31 LGGRIVGGTASSI---ED-----RPWQVSLQRSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNLR 87
            :.|.:|.|:.|.|   ||     :|||.:|......||.|.::....:::||||.....|: .|.
Human    19 VAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTI-GLG 82

  Fly    88 IRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTFGSTIKAITMASATPAHGSA 152
            :.:....:..|..:||.:....|..||.....||:.:::|...::...||::|::||..|..|::
Human    83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS 147

  Fly   153 ASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAAA--TNKDACQGDSG 215
            ..:||||..: :|.....|..|:..:|....|...   |......:|.||..  ..||:|.||||
Human   148 CLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKL---YDPLYHPSMFCAGGGQDQKDSCNGDSG 208

  Fly   216 GPLVSGGQLVGVVSWGR-DCAVANYPGVYANIAELRDWVLQAQKTV 260
            |||:..|.|.|:||:|: .|.....||||.|:.:..:|:   :|||
Human   209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI---EKTV 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	70/228 (31%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	68/226 (30%)