Protein Alignment Ser8 and Tmprss5

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001346389.1
• Gene: Tmprss5 / 80893
• MGIID: 1933407
• Length: 455
• Species: Mus musculus
• Alignment Length: 259
• Identity: 96/259 - (37%)
• Similarity: 136/259 - (52%)
• Gaps: 29/259 - (11%)

  Fly    16 NGAVIPI-----GLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAH 75
            :|.::.:     |..|    |..|||||.|.:....|||.|:.....|.||.|:::.:.:|||||
Mouse   198 SGRIVSLKCSECGARP----LASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPHWVVTAAH 258

  Fly    76 CLDT--PTTVSNLRIRAG----SNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTFG 134
            |:.:  .:.:|:.|:.||    ...|.:.|.:||  .|..|..|::.:...|:.:::|:|.:.|.
Mouse   259 CMYSFRLSRLSSWRVHAGLVSHGAVRQHQGTMVE--KIIPHPLYSAQNHDYDVALLQLRTPINFS 321

  Fly   135 STIKAITMASATPAH---GSAASISGWGKTS-TDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFI 195
            .|:.|:.: .|...|   ||...:||||.|. :...||.||......::....|.||.. |...:
Mouse   322 DTVGAVCL-PAKEQHFPWGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTYLCNSSCM-YSGAL 384

  Fly   196 KATMICAAATN--KDACQGDSGGPLV--SGG--QLVGVVSWGRDCAVANYPGVYANIAELRDWV 253
            ...|:||...:  .||||||||||||  ||.  .|||||||||.||..|.|||||.:||..||:
Mouse   385 THRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	90/233 (39%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:464747	2/14 (14%)
		Tryp_SPc	217..448	CDD:214473	91/234 (39%)