DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser8 and prss60.1

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	265	Identity:	97/265 - (36%)
Similarity:	140/265 - (52%)	Gaps:	29/265 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LALLALTNGAVIPI---GLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRS--GSHFCGGSIISNN 68
            ||||....|:...:   ||.|    |..|||||..:.....||||||...  |.||||||:|::.
Zfish     9 LALLLCVQGSHSQLNVCGLAP----LNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSE 69

  Fly    69 IIVTAAHCLDTPTTVSNLRIRAGSNKRTYGGVLV-----EVAAIKAHEAYNSNSKINDIGVVRLK 128
            .::||||||...|| |:|.:..|  |.|..||..     .|:.|..|.:||:.:..|||.::.|.
Zfish    70 WVLTAAHCLPRITT-SSLLVFLG--KTTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLS 131

  Fly   129 TKLTFGSTIKAITMASATPA--HGSAASISGWG--KTSTDGPSSATLLFVDTRIVGRSQCGSSTY 189
            :.:||.:.|:.:.:|:....  :|:::.|:|||  :...:.|:...|......:|...|| ::..
Zfish   132 SAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQC-NALL 195

  Fly   190 GYGSFIKATMICAAAT--NKDACQGDSGGPLVSGGQLV----GVVSWGRDCAVANYPGVYANIAE 248
            |.|| :...||||...  .:|.||||||||:||...||    |:.|||..||....||||..:::
Zfish   196 GSGS-VTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQ 259

  Fly   249 LRDWV 253
            .:.|:
Zfish   260 YQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	87/235 (37%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	86/234 (37%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	87/235 (37%)
		Tryp_SPc	34..267	CDD:238113	87/236 (37%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910