Protein Alignment Ser8 and KLK10

DIOPT Version :9

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001070968.1
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 71/282 - (25%)
• Similarity: 118/282 - (41%)
• Gaps: 58/282 - (20%)

  Fly     1 MSLLIATFLALLALTNGAVIP---IGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGG 62
            ::.|:...:|.|.....|::|   ..|:|:..        |:..:...:||||||....|..|.|
Human    17 LAKLLPLLMAQLWAAEAALLPQNDTRLDPEAY--------GSPCARGSQPWQVSLFNGLSFHCAG 73

  Fly    63 SIISNNIIVTAAHCLDTPTTVSNLRIRAGSN----------KRTYGGVLVEVAAIKAHEAYNSNS 117
            .::..:.::|||||.:.|     |..|.|.:          :||...|:        |..|:..|
Human    74 VLVDQSWVLTAAHCGNKP-----LWARVGDDHLLLLQGEQLRRTTRSVV--------HPKYHQGS 125

  Fly   118 --------KINDIGVVRLKTKLTFGSTIKAITMASATPAHGSAASISGWGKTS------TDGPSS 168
                    ..:|:.:::|...:..|..::|:.:.......|....::|||.|:      ..|.:.
Human   126 GPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTC 190

  Fly   169 ATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAAA-TNKDACQGDSGGPLVSGGQLVGVVSWG- 231
            :::     .|:...:|   ...|...:...||||.. ..:|.||.|||||||....|.|::|||
Human   191 SSI-----TILSPKEC---EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGV 247

  Fly   232 RDCAVANYPGVYANIAELRDWV 253
            ..|..|.:|.||..|.:...|:
Human   248 YPCGSAQHPAVYTQICKYMSWI 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	63/244 (26%)
		Tryp_SPc	35..253	CDD:238113	63/243 (26%)
KLK10	NP_001070968.1	Tryp_SPc	49..272	CDD:238113	64/242 (26%)
		Tryp_SPc	49..269	CDD:214473	63/240 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920