Protein Alignment Ser8 and PRSS2

DIOPT Version :9

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 95/268 - (35%)
• Similarity: 133/268 - (49%)
• Gaps: 35/268 - (13%)

  Fly     3 LLIATFLALLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISN 67
            |||.||:|       |.:....:..     .:||||........|:|||| .||.||||||:||.
Human     4 LLILTFVA-------AAVAAPFDDD-----DKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISE 55

  Fly    68 NIIVTAAHCLDTPTT---------VSNLRIRAGS-NKRTYGG--VLVEVAAIKAHEAYNSNSKIN 120
            ..:|:|.||..:...         ...:::|.|. |.....|  ..:..|.|..|..|||.:..|
Human    56 QWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN 120

  Fly   121 DIGVVRLKTKLTFGSTIKAITMASATPAHGSAASISGWGKTSTDG---PSSATLLFVDTRIVGRS 182
            ||.:::|.:.....|.:.||::.:|.||.|:.:.|||||.|.:.|   |..  |..:|..::.::
Human   121 DILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDE--LQCLDAPVLSQA 183

  Fly   183 QCGSSTYGYGSFIKATMICAA--ATNKDACQGDSGGPLVSGGQLVGVVSWGRDCAVANYPGVYAN 245
            :|.:|   |...|...|.|..  ...||:||||||||:||.|:|.|:||||..||..|.||||..
Human   184 ECEAS---YPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTK 245

  Fly   246 IAELRDWV 253
            :....||:
Human   246 VYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	87/235 (37%)
		Tryp_SPc	35..253	CDD:238113	87/234 (37%)
PRSS2	NP_001290343.1	Tryp_SPc	23..253	CDD:214473	87/235 (37%)
		Tryp_SPc	24..256	CDD:238113	88/236 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8473
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920