Protein Alignment Ser8 and PRSS1

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 89/260 - (34%)
• Similarity: 131/260 - (50%)
• Gaps: 33/260 - (12%)

  Fly     3 LLIATFLALLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISN 67
            |||.||:|       |.:....:..     .:||||........|:|||| .||.||||||:|:.
Human     4 LLILTFVA-------AALAAPFDDD-----DKIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINE 55

  Fly    68 NIIVTAAHCLDTPTTV----SNLRIRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLK 128
            ..:|:|.||..:...|    .|:.:..|:.:      .:..|.|..|..|:..:..|||.:::|.
Human    56 QWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQ------FINAAKIIRHPQYDRKTLNNDIMLIKLS 114

  Fly   129 TKLTFGSTIKAITMASATPAHGSAASISGWGKTSTDG---PSSATLLFVDTRIVGRSQCGSSTYG 190
            ::....:.:..|::.:|.||.|:...|||||.|::.|   |..  |..:|..::.:::|.:|
Human   115 SRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDE--LQCLDAPVLSQAKCEAS--- 174

  Fly   191 YGSFIKATMICAA--ATNKDACQGDSGGPLVSGGQLVGVVSWGRDCAVANYPGVYANIAELRDWV 253
            |...|.:.|.|..  ...||:||||||||:|..|||.||||||..||..|.||||..:.....|:
Human   175 YPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWI 239

  Fly   254  253
            Human   240  239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	81/226 (36%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	81/227 (36%)