Protein Alignment Ser8 and KLK15

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 85/274 - (31%)
• Similarity: 124/274 - (45%)
• Gaps: 41/274 - (14%)

  Fly     4 LIATFLALLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNN 68
            |:.|...|||.|            .:..|.:::.|...:...:||||:|...|...||.|:||.:
Human     3 LLLTLSFLLAST------------AAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPH 55

  Fly    69 IIVTAAHCLDTPTTV----SNLRIRAGSNK-RTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLK 128
            .:::||||......|    .|||.|.|..: ||...|:       .|..|.:.|..|||.::||.
Human    56 WVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVI-------PHPRYEARSHRNDIMLLRLV 113

  Fly   129 TKLTFGSTIKAITMASATPAHGSAASISGWGKTSTDGPSSA-----------TLLFVDTRIVGRS 182
            ........::...:.:..|..|.|..:||||..|.:.|.:|           ||...:..|:..:
Human   114 QPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178

  Fly   183 QCGSSTYGYGSFIKATMICAAATNK--DACQGDSGGPLVSGGQLVGVVSWGR-DCAVANYPGVYA 244
            .|..|   |...:..||:||.|..:  ::|:||||||||.||.|.|:||||. .|.....||||.
Human   179 SCDKS---YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYT 240

  Fly   245 NIAELRDWVLQAQK 258
            .:....:|:.:..|
Human   241 KVCHYLEWIRETMK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	76/236 (32%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	76/233 (33%)