Protein Alignment Ser8 and ACR

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 91/286 - (31%)
• Similarity: 135/286 - (47%)
• Gaps: 42/286 - (14%)

  Fly     2 SLLIATFLALLALTNGAVI-PIGLEPQTSSLGG-RIVGGTASSIEDRPWQVSLQ-----RSGSHF 59
            ::|:...::::|..|.... |.||..:.:..|| |||||.|:.....||.||||     ....|.
Human     8 AILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHT 72

  Fly    60 CGGSIISNNIIVTAAHCLDTPTTVSNLRIRAGSNKRTYG------GVLVE--VAAIKAHEAYNSN 116
            ||||::::..::|||||......|.:.|:..|:.:.|||      ..|.|  |..|..||.|||.
Human    73 CGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSA 137

  Fly   117 SKINDIGVVRLKTKLTFGSTI--------KAITMASATPAHGSAASISGWGKTSTDGPSSATLLF 173
            ::.|||.:|.:...::.|..|        ||     ..|....:..::|||......|..:::|.
Human   138 TEGNDIALVEITPPISCGRFIGPGCLPHFKA-----GLPRGSQSCWVAGWGYIEEKAPRPSSILM 197

  Fly   174 ---VDTRIVGRSQCGSSTYGYGSFIKATMICAA--ATNKDACQGDSGGPLV------SGGQLVGV 227
               ||  ::....| :||..|...::.|.:||.  ....|.|||||||||:      |...:||:
Human   198 EARVD--LIDLDLC-NSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGI 259

  Fly   228 VSWGRDCAVANYPGVYANIAELRDWV 253
            .|||..||.|..||:|.......:|:
Human   260 TSWGVGCARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	81/249 (33%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	82/250 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421