DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser8 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	90/256 - (35%)
Similarity:	131/256 - (51%)	Gaps:	32/256 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GLEPQTSSLGG-RIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNL 86
            |...:|.:.|| ::.||..:...:.|||.|||::..|.||.::|||:.::|||||.
  Rat   174 GCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCF--------- 229

  Fly    87 RIRAGSNKR---TYGGVLVE------VAAIKAHEAYNSNSKINDIGVVRLKTKLTFGSTIKAITM 142
             :|:.:.|.   ::|.:|.:      |.:|..||.|:..:..|||.||||.:.:.:.:.|:...:
  Rat   230 -VRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACL 293

  Fly   143 ASATPAH--GSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAA-- 203
            ..||...  .|...::|||...:||.|...|.....:|:....|.|.. .||..|...|:||.
  Rat   294 PEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGK-AYGGVITPGMLCAGFL 357

  Fly   204 ATNKDACQGDSGGPLVSGGQ-----LVGVVSWGRDCAVANYPGVYANIAELRDWVLQAQKT 259
            ....|||||||||||||...     |.|:||||.:||:.|.||||..:...|||:  :.||
  Rat   358 EGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI--SSKT 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	83/236 (35%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	83/235 (35%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	83/236 (35%)
		Tryp_SPc	187..415	CDD:238113	84/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920