Protein Alignment Ser8 and PRSS57

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 68/257 - (26%)
• Similarity: 114/257 - (44%)
• Gaps: 24/257 - (9%)

  Fly    11 LLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAH 75
            ||.:....::|:  :|...|.|.:|:||...:...||:..|::..|.|.|||.::....:|:|||
Human    12 LLTVATALMLPV--KPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAH 74

  Fly    76 C-----LDTPTTVSNLRI--RAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTF 133
            |     |.|...|....:  .|...::.:|     :.|:..|..|:..:..|||.::||......
Human    75 CFSHRDLRTGLVVLGAHVLSTAEPTQQVFG-----IDALTTHPDYHPMTHANDICLLRLNGSAVL 134

  Fly   134 GSTIKAIT---MASATPAHGSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFI 195
            |..:..:.   ..:..|..|:...::|||..|........|:....|::....|.||..|:   :
Human   135 GPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH---L 196

  Fly   196 KATMICAAATN---KDACQGDSGGPLVSGGQLVGVVSW-GRDCAVANYPGVYANIAELRDWV 253
            ..||:|..:.:   :..|..|||||||...:..|:||: |..|.....|.||..::....|:
Human   197 TLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	61/231 (26%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	61/231 (26%)