DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser8 and ovch1

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_956439.2	Gene:	ovch1 / 393114	ZFINID:	ZDB-GENE-040426-834	Length:	556	Species:	Danio rerio

Alignment Length:	263	Identity:	80/263 - (30%)
Similarity:	129/263 - (49%)	Gaps:	26/263 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LTNGAVIPIGLE---PQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAH 75
            |..|..:..|:.   |:......||:||..:.....|||||||.:....|||:|:....::||.|
Zfish    33 LDKGCDVLAGIRSFVPEDEVEESRIIGGKEAWAHSWPWQVSLQYNDVPTCGGAILDQLWVITAGH 97

  Fly    76 CL---------DTPTTVSNLRIRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKL 131
            |.         :....:.||.....|::.:     ::|..|.:|:.||..:..|||.:::|::.|
Zfish    98 CFKRYKKPSMWNAVVGLHNLDNANESSRES-----IQVQKIFSHKNYNQKTNENDIALLKLQSPL 157

  Fly   132 TFGSTIKAITMASATPAHGSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIK 196
            .|...::.|.:.:.........:::|||..:.:||.::.|..|:..:....:|  :.:..|..:|
Zfish   158 VFSKFVRPIGVFNNDLPPLVTCTVTGWGSVTENGPQASRLQEVNVTVYEPQKC--NRFYRGKVLK 220

  Fly   197 ATMICAAAT--NKDACQGDSGGPL--VSGG--QLVGVVSWGRDCAVANYPGVYANIAELRDWVLQ 255
             :||||.|.  ..|||||||||||  ..|.  :|.||||||..|..|..||||..:...|.|::.
Zfish   221 -SMICAGANEGGMDACQGDSGGPLSCFDGERYKLAGVVSWGVGCGRAQKPGVYTTLYHYRQWMVS 284

  Fly   256 AQK 258
            :.:
Zfish   285 SMR 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	75/233 (32%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	74/232 (32%)
ovch1	NP_956439.2	Tryp_SPc	56..281	CDD:214473	75/232 (32%)
		Tryp_SPc	57..281	CDD:238113	74/231 (32%)
		Tryp_SPc	331..551	CDD:238113
		Tryp_SPc	331..549	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910