Protein Alignment Ser8 and KLK2

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 111/263 - (42%)
• Gaps: 38/263 - (14%)

  Fly    12 LALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAHC 76
            :||:.|..   |..|...|   |||||.......:||||::...|...|||.::....::|||||
Human     8 IALSVGCT---GAVPLIQS---RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC 66

  Fly    77 LDTPTTV----SNLRIRAGSNKRTYGGVLVEVAAIKAHEAYN-----------SNSKINDIGVVR 126
            |...:.|    .||.....:.:|      |.|:....|..||           .....:|:.::|
Human    67 LKKNSQVWLGRHNLFEPEDTGQR------VPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125

  Fly   127 LKTKLTFGSTIKAITMASATPAHGSAASISGWGKTSTD---GPSSATLLFVDTRIVGRSQCGSST 188
            |.........:|.:.:.:..||.|:....||||....:   .|.|  |..|...::....|..:
Human   126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRS--LQCVSLHLLSNDMCARA- 187

  Fly   189 YGYGSFIKATMICAA--ATNKDACQGDSGGPLVSGGQLVGVVSWGRD-CAVANYPGVYANIAELR 250
              |...:...|:||.  ...||.|.||||||||..|.|.|:.|||.: ||:...|.||..:...|
Human   188 --YSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250

  Fly   251 DWV 253
            .|:
Human   251 KWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	70/238 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	71/240 (30%)