DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser8 and Prss3

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001102096.1	Gene:	Prss3 / 362347	RGDID:	1311446	Length:	246	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	91/260 - (35%)
Similarity:	134/260 - (51%)	Gaps:	28/260 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LALLALTNGAV-IPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVT 72
            |..|||...|| .|:..:       .:||||........|:|||| .||.||||||:|::..:|:
  Rat     4 LLFLALVGVAVAFPVDDD-------DKIVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVS 60

  Fly    73 AAHCLDTPTTV----SNLRIRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTF 133
            ||||..|...|    .|:.:..|..:      .|..|.|..|..:|:.:..|||.:::|.:.:..
  Rat    61 AAHCYKTRIQVRLGEHNINVLEGDEQ------FVNAAKIIKHPNFNARNLNNDIMLIKLSSPVKL 119

  Fly   134 GSTIKAITMASATPAHGSAASISGWGKTSTDGPSSATLL-FVDTRIVGRSQCGSSTYGYGSFIKA 197
            .:.:..:.:.|:....|:...|||||.|.:.|.::..|| .:|..::.::.|.:|   |...|..
  Rat   120 NARVATVALPSSCAPAGTQCLISGWGNTLSLGVNNPDLLQCLDAPVLPQADCEAS---YPGKITN 181

  Fly   198 TMICAA--ATNKDACQGDSGGPLVSGGQLVGVVSWGRDCAVANYPGVYANIAELRDWVLQAQKTV 260
            .|||..  ...||:||||||||:|..|||.|:||||..||:.:.||||..:....||:   |.|:
  Rat   182 NMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALKDNPGVYTKVCNYVDWI---QDTI 243

Fly 261 260
Rat 244 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	81/225 (36%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	81/224 (36%)
Prss3	NP_001102096.1	Tryp_SPc	23..239	CDD:214473	81/225 (36%)
Prss3	NP_001102096.1	Tryp_SPc	24..242	CDD:238113	83/230 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I4263
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8948
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.870