Protein Alignment Ser8 and KLK3

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 73/263 - (27%)
• Similarity: 110/263 - (41%)
• Gaps: 33/263 - (12%)

  Fly     8 FLALLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVT 72
            ||.|      :|..||..|...|   |||||.......:||||.:...|...|||.::....::|
Human     7 FLTL------SVTWIGAAPLILS---RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLT 62

  Fly    73 AAHCLDTPTTVSNLRIRAGSNKRTYGGVLVEVAAIKAHEAYN-----------SNSKINDIGVVR 126
            ||||:...:.:...|......:.|  |.:.:|:....|..|:           .:...:|:.::|
Human    63 AAHCIRNKSVILLGRHSLFHPEDT--GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125

  Fly   127 LKTKLTFGSTIKAITMASATPAHGSAASISGWGKTSTD---GPSSATLLFVDTRIVGRSQCGSST 188
            |.........:|.:.:.:..||.|:....||||....:   .|..  |..||..::....|...
Human   126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKK--LQCVDLHVISNDVCAQV- 187

  Fly   189 YGYGSFIKATMICAA--ATNKDACQGDSGGPLVSGGQLVGVVSWGRD-CAVANYPGVYANIAELR 250
              :...:...|:||.  ...|..|.||||||||..|.|.|:.|||.: ||:...|.:|..:...|
Human   188 --HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYR 250

  Fly   251 DWV 253
            .|:
Human   251 KWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	63/234 (27%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	64/236 (27%)