DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser8 and Prss53

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	270	Identity:	78/270 - (28%)
Similarity:	133/270 - (49%)	Gaps:	42/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GAVIPI-GLEPQTSSLGGR-------IVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTA 73
            |||:.| ||:....:.|.|       ..|.|...  :.|||.|::|.|.|.|.||::::..::||
Mouse    13 GAVVVIEGLQAAQRACGQRGPGPPEPQEGNTLPG--EWPWQASVRRQGVHICSGSLVADTWVLTA 75

  Fly    74 AHCLDTPTT--VSNLRIRAGSNK---RTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTF 133
            |||.:...|  :|:..:..||.|   ::.|...|.|||::..:|||..|:.:|:.:::|.
Mouse    76 AHCFEKMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLT----- 135

  Fly   134 GSTIKAITMASATPAH----GSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYG---- 190
            ..|::. |:....|.:    |::...:||.:.::|  .|.||..:..|::.|..| :..|.
Mouse   136 HPTVQT-TLCLPQPTYHFPFGASCWATGWDQNTSD--VSRTLRNLRLRLISRPTC-NCLYNRLHQ 196

  Fly   191 --YGSFIKATMICAAAT--NKDACQGDSGGPLV----SGGQL-VGVVSWGRDCAVANYPGVYANI 246
              ..:..:..|:|..|.  .:..||||||||::    .|..: ||::|:...||..:.|.:..::
Mouse   197 RLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCAQEDTPVLLTDM 261

  Fly   247 AELRDWVLQA 256
            |....| |||
Mouse   262 AVHSSW-LQA 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	67/247 (27%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	66/239 (28%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		4/18 (22%)
		Tryp_SPc	45..271	CDD:238113	68/238 (29%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030