DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser8 and CG32834

DIOPT Version :9

Sequence 1:	NP_610874.1	Gene:	Ser8 / 36489	FlyBaseID:	FBgn0019928	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001188996.1	Gene:	CG32834 / 318238	FlyBaseID:	FBgn0052834	Length:	556	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	83/270 - (30%)
Similarity:	126/270 - (46%)	Gaps:	33/270 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLIATFLALLALTNGAVIPIGLEPQTSSLG--GRIVGGTASSIEDRPWQVSLQRSGSHFCGGSII 65
            ::.:.||.|||..        |.|....|.  .||:||....|||.|:|..:...|:..|.|:||
  Fly     1 MIWSVFLFLLAAL--------LRPVRGDLDAQSRIIGGYDVDIEDAPYQAEVIIDGTAICSGAII 57

  Fly    66 SNNIIVTAAHCLDTPTTVSNLRIRAGSNKRTYGGV--LVEVAAIKAHEAYNSNSKINDIGVVRLK 128
            :::.|:|||.|:.   :..::.:|.|::.|.|.|.  |:||..|..|..||.....|::.:::|.
  Fly    58 TSDTIITAASCVQ---SYGSIEVRVGTSSRDYDGTGFLLEVCEIINHPQYNCWRFDNNLALLKLC 119

  Fly   129 TKLTFGSTIKAITMASATPAHGSAASISGWGKTSTDG----------PSSATLLFVDTRIVGRSQ 183
            ..|.....|:.|::|...|..||..::||||.||..|          |....:.:|.  :..|.|
  Fly   120 DPLKTSEAIQPISIAEDEPDDGSWCTVSGWGSTSWWGSWWDRCFGSLPDYLQMAWVS--VYNREQ 182

  Fly   184 CGSST-YGYGSFIKATMICAAATNKDA--CQGDSGGPLVSGGQLVGVVSWGRDCAVANYPGVYAN 245
            |.:.. ..:|.:..........|:..|  |..|:|.|||..|||||::|.| .|...  |.||||
  Fly   183 CAADRGVWFGLWDNGISYLTLCTHNGAGGCSYDTGAPLVIDGQLVGILSEG-GCTTK--PDVYAN 244

  Fly   246 IAELRDWVLQ 255
            :.....|:.:
  Fly   245 VPWFTGWIAE 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	34..253	CDD:214473	74/233 (32%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	73/232 (31%)
CG32834	NP_001188996.1	Tryp_SPc	26..252	CDD:214473	74/233 (32%)
		Tryp_SPc	27..255	CDD:238113	74/236 (31%)
		BES1_N	<293..343	CDD:283367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000678
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010