Protein Alignment Ser8 and GZMA

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 70/262 - (26%)
• Similarity: 122/262 - (46%)
• Gaps: 25/262 - (9%)

  Fly    12 LALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAHC 76
            ||.:...|:.:.|.|:  .:..:|:||...:...||:.|.|.......|.|::|:.:.::|||||
Human     8 LASSLSVVVSLLLIPE--DVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC 70

  Fly    77 LDTPTTVSNLRIRA----GSNKRTYGGVLVEVAAIK---AHEAYNSNSKINDIGVVRL--KTKLT 132
                    ||..|:    |::..|......::..:|   .:..|:..::..|:.:::|  |.|:.
Human    71 --------NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKIN 127

  Fly   133 FGSTIKAITMASATPAHGSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGS-STYGYGSFIK 196
            ...||..:.........|:...::|||:|......|.||..|:..|:.|..|.. :.|.:...|.
Human   128 KYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192

  Fly   197 ATMICAAAT--NKDACQGDSGGPLVSGGQLVGVVSWGRD--CAVANYPGVYANIAELR-DWVLQA 256
            ..|:||.:.  .:|:|.||||.||:..|...||.|:|.:  |.....||||..:::.. :|::..
Human   193 MNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257

  Fly   257 QK 258
            .|
Human   258 IK 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	63/232 (27%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	63/232 (27%)