Protein Alignment Ser8 and Tmprss13

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: XP_006510195.1
• Gene: Tmprss13 / 214531
• MGIID: 2682935
• Length: 561
• Species: Mus musculus
• Alignment Length: 529
• Identity: 94/529 - (17%)
• Similarity: 165/529 - (31%)
• Gaps: 180/529 - (34%)

  Fly    57 DWSDNTYPQHKLEGVTSKIPRFNWTVMYAHPVKPGTYQATITVKKTFVVIPYELKSATISFN-LT 120
            |.:|...|.|:     |:..:..:.::|.|.:          ::.....:|..|...||:.| .|
Mouse    55 DGTDFDNPVHR-----SRKWQRRFFILYEHGL----------LRYALDEMPTTLPQGTINMNQCT 104

  Fly   121 SMLNGQLMLTQNDTVVNST-------------YVSSTLPLNQTIALSESDHRALSRAAYVQTFWF 172
            .:::|:....|..::...|             .:|..|.:......:...::...|.....|
Mouse   105 DVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPT--- 166

  Fly   173 INCQYIGTSDELSTLSNFTQENSTYTVEALVVASFEKLPEPTTTTTTTTTTTTTTTTTTTTTTTT 237
              .|..|.:....|.|:.....|:.:..:..:.|.||:|   ||.:|..............|:.:
Mouse   167 --PQEPGPAKMAVTSSSGGSSGSSSSSSSSSIPSAEKVP---TTKSTLWQEEMRAKDQPDGTSLS 226

  Fly   238 PATTTSTSTTTTTSTP----------------------------------------------TPP 256
            |..:.|.|......||                                              .||
Mouse   227 PVQSPSQSQPPAACTPRETGLDSKEDENILSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPP 291

  Fly   257 -TTTSSTTTPATTTS------------------------TTPKSTTSTTKS-----PAVSDGSGS 291
             .:..|.:||.:..|                        |||.|.|...:|     |...|.:..
Mouse   292 LLSPPSPSTPHSRRSQVIEKFEALDIEKAEHMETNMLILTTPSSDTRQGRSERRAIPRKRDFASE 356

  Fly   292 --TGP-SDA------RRKRDTERELLIGSNQTSNVLDGISPALLN-----LTDRNSKFRWPL-YI 341
              |.| |||      ||.:..:|.    |.::|     ::|.|||     ||.:....:|.. :.
Mouse   357 TPTAPLSDACPLSPHRRAKSLDRR----STESS-----MTPDLLNFKKGWLTKQYEDGQWKKHWF 412

  Fly   342 ILPDVS----KETVMEASPNQDPFLRIAKKSDRFYNLEDARQPYICDNSSMVAPDP-KKVYGYFQ 401
            :|.|.|    :::|.|.:.:.|..:.::...|                   |...| ::.||
Mouse   413 VLADQSLRYYRDSVAEEAADLDGEINLSTCYD-------------------VTEYPVQRNYG--- 455

  Fly   402 RTFTVQHPIARFNVSG------QQWVRQGQPVDLVFQCSGTPPFEFCYNLNHGQHNMTSNETCKS 460
              |.:......|.:|.      :.|::     .::.....|...:...:|..|::..||.:||
Mouse   456 --FQIHTKEGEFTLSAMTSGIRRNWIQ-----TIMKHVLPTSAPDVTSSLPEGKNKSTSFDTC-- 511

  Fly   461 GWEPSRTAE 469
             ..||...|
Mouse   512 -LRPSEKQE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	36/209 (17%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065	15/81 (19%)
		SRCR_2	225..315	CDD:464747	11/89 (12%)
		Tryp_SPc	319..548	CDD:214473	50/242 (21%)