Protein Alignment Ser8 and CFD

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 69/232 - (29%)
• Similarity: 118/232 - (50%)
• Gaps: 18/232 - (7%)

  Fly    33 GRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNLRIRAGS----- 92
            |||:||..:....||:..|:|.:|:|.|||.:::...:::|||||:.... ..:::..|:
Human    31 GRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAAD-GKVQVLLGAHSLSQ 94

  Fly    93 ---NKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTFGSTIKAI--TMASATPAHGSA 152
               :||.|     :|.....|.....::..:|:.:::|..|.|.|..::.:  .......|.|:.
Human    95 PEPSKRLY-----DVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTL 154

  Fly   153 ASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAAATNKDACQGDSGGP 217
            ..::|||..:..|....:|..|...::.|:.|...|:..|: |...::||.:..:|:|:||||||
Human   155 CDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGA-ITERLMCAESNRRDSCKGDSGGP 218

  Fly   218 LVSGGQLVGVVSWG-RDCAVANYPGVYANIAELRDWV 253
            ||.||.|.|||:.| |.|.....||:|..:|....|:
Human   219 LVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	66/228 (29%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	67/230 (29%)