Protein Alignment Ser8 and Cfd

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 259
• Identity: 75/259 - (28%)
• Similarity: 131/259 - (50%)
• Gaps: 29/259 - (11%)

  Fly     8 FLALLALTNGAVIPIGLEPQTSSLGGRIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVT 72
            |:||:.|  ||.: ...:|:     |||:||..::...||:..|:|.:|:|.|||:::....:::
Mouse     7 FVALVIL--GAAV-CAAQPR-----GRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLS 63

  Fly    73 AAHCLDTPTTVSNLRIRAGSN--------KRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKT 129
            ||||:|..|...::::..|::        ||.|     :|.::..|.....:|..:|:.:.:|..
Mouse    64 AAHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWY-----DVQSVVPHPGSRPDSLEDDLILFKLSQ 123

  Fly   130 KLTFGSTIKAITM----ASATPAHGSAASISGWGKTSTDGPSSATLLFVDTRIVGRSQCGSSTYG 190
            ..:.|..::.:.:    ....|  |:...::|||..:..|.....|..:...|:.|:.|...||
Mouse   124 NASLGPHVRPLPLQYEDKEVEP--GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY- 185

  Fly   191 YGSFIKATMICAAATNKDACQGDSGGPLVSGGQLVGVVSWG-RDCAVANYPGVYANIAELRDWV 253
            :...:...|:||.:..:|.|:||||.|||.|..:.|||:|| |.|.....||||..::..|.|:
Mouse   186 HDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	65/230 (28%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	66/232 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)