Protein Alignment Ser8 and PRSS21

DIOPT Version :10

• Sequence 1: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 93/287 - (32%)
• Similarity: 130/287 - (45%)
• Gaps: 40/287 - (13%)

  Fly     6 ATFLALLALTNGAVIPIGLE--PQTSSLG-----GRIVGGTASSIEDRPWQVSLQRSGSHFCGGS 63
            |..||||....|...|...|  |.:...|     .|||||..:.:...|||.||:...||.||.|
Human     6 ALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVS 70

  Fly    64 IISNNIIVTAAHCLDTPTTVSNLRIRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKIN-------- 120
            ::|:...:|||||.:|.:.:|:     .|......|.|..:.:..:.:||.:...::
Human    71 LLSHRWALTAAHCFETYSDLSD-----PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY 130

  Fly   121 ------DIGVVRLKTKLTFGSTIKAITMASATPAHGSAAS--ISGWGKTSTDG--PSSATLLFVD 175
                  ||.:|:|...:|:...|:.|.:.::|....:...  ::|||....|.  ||..||..|.
Human   131 LGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQ 195

  Fly   176 TRIVGRSQCGS--STYGYGSFIKATMICA--AATNKDACQGDSGGPLVSGGQ----LVGVVSWGR 232
            ..|:..|.|..  ..|.:...|...|:||  |...||||.|||||||.....    .:||||||.
Human   196 VAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGV 260

  Fly   233 DCAVANYPGVYANIAELRDWV--LQAQ 257
            .|...|.||||.||:...:|:  |.||
Human   261 GCGRPNRPGVYTNISHHFEWIQKLMAQ 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	78/243 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	79/245 (32%)