Protein Alignment ATP8A and AT1G54280

DIOPT Version :10

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: NP_175830.1
• Gene: AT1G54280 / 841869
• AraportID: AT1G54280
• Length: 1240
• Species: Arabidopsis thaliana
• Alignment Length: 1212
• Identity: 460/1212 - (37%)
• Similarity: 672/1212 - (55%)
• Gaps: 144/1212 - (11%)

  Fly   214 GERRIINLNGPQ---PTK---YGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPE 272
            |..||::.|.|.   .||   |.:|.::|.:|:.::|||..|:|||.|.:|.:||:.|||...|
plant    38 GYTRIVHCNQPHLHLATKLIRYRSNYVSTTRYNLLTFLPKCLYEQFHRVANFYFLVAAILSVFP- 101

  Fly   273 VSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHR--SIERLDSGSWCTVRWSELTVGD 335
            :||..:::.:.||:|::.:|..||.:||.:|...|.|:|.|  |:.: .||.:....|..:.|||
plant   102 LSPFNKWSMIAPLVFVVGLSMGKEALEDWRRFMQDVEVNSRKASVHK-GSGDFGRRTWKRIRVGD 165

  Fly   336 IIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRIE 400
            |::|..:.||||||:|||||....:|::||.|||||||||:::.|.||..|.:.:..|...|.|:
plant   166 IVRVEKDEFFPADLLLLSSSYEDGICYVETMNLDGETNLKVKRCLDATLALEKDESFQNFSGTIK 230

  Fly   401 CELPNRHLYEFNGVLRETGK--PPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSA 463
            ||.||.:||.|.|.|...|:  |   |..:|:|.|.:.|||||:|:|:||::|.:||:|:|||.:
plant   231 CEDPNPNLYTFVGNLECDGQVYP---LDPNQILLRDSKLRNTAYVYGVVVFTGHDTKVMQNSTKS 292

  Fly   464 PLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLTDFKTKSLG------- 521
            |.|||.::|..:..|..||.:|:::..||.|.....|:......||  |...|.:||.
plant   293 PSKRSRIEKRMDYIIYTLFALLLTVSFISSLGFAVMTKLLMAEWWY--LRPDKPESLTNPTNPLY 355

  Fly   522 ---YNLLTFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMV 583
               .:|:|..:||..||||||.|::|:|:.|||.|||.|:::|..||.|||.|||||||||||.|
plant   356 AWVVHLITALLLYGYLIPISLYVSIEVVKVLQAHFINQDLQLYDSESGTPAQARTSNLNEELGQV 420

  Fly   584 KYIFSDKTGTLTQNVMEFKKCSIAG---------------------------------------- 608
            ..|.||||||||.|.|:|.||||||
plant   421 DTILSDKTGTLTCNQMDFLKCSIAGTSYGVRASEVELAAAKQMAMDLEEKGEEVANLSMNKGRTQ 485

  Fly   609 -YVYTAERTPEESQLVQNILGRHE----------------------------TSAVIEEFLELLS 644
             |...|.:|..:.:|...:....|                            .|..|..|..:|:
plant   486 RYAKLASKTSSDFELETVVTASDEKDQKQNTGVKGFSFEDNRLMNENWLNEPNSDDILMFFRILA 550

  Fly   645 VCHTVIPERKEN-GNMIYHAASPDERALVEGAQKFGYIFDTRTPKYVEI------NALGVRKRYE 702
            ||||.|||..|: |...|.|.||||.|.:..:::||:.|..||...|.|      :...|.:.|:
plant   551 VCHTAIPEVDEDTGMCTYEAESPDEVAFLVASREFGFEFTKRTQSSVFIAERFSSSGQPVDREYK 615

  Fly   703 VLNVLEFTSSRKRMSLIVRTPENKIKLFCKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRT 767
            :||:|:|||.|||||.|||..|.:|.|.|||||::|:|||:..|:.:...|.:||..:...||||
plant   616 ILNLLDFTSKRKRMSAIVRDEEGQILLLCKGADSIIFERLSKSGKEYLGATSKHLNVYGEAGLRT 680

  Fly   768 LCLAVADIRPDVYQEWSQTFDKASVAL-QNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPET 831
            |.|....:....|..|:..|.||..:: .:|:..||..::::|..|.|:||||:||:||.|||:.
plant   681 LALGYRKLDETEYAAWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILVGATAVEDKLQKGVPQC 745

  Fly   832 IASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSM---DIIILNEESLDATREVIHRHYGEFKS 893
            |.:|..||:.||||||||.||||||||:|.|:...|   .|.:.|.|......|...:.....:.
plant   746 IDNLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQISISLTNVEESSQNSEAAAKESILMQI 810

  Fly   894 SSA-------KD--ANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMV 949
            ::|       ||  |..||:|||.||.|||..|::..|..|.:.|..||||||||.|||.|..:.
plant   811 TNASQMIKIEKDPHAAFALIIDGKTLTYALKDDVKYQFLALAVDCASVICCRVSPKQKALVTRLA 875

  Fly   950 TQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYA 1014
            .:.|...|||||||||||.|||:|::|:|||||||:||..|||:||||||:|:|||:|||.|.|.
plant   876 KEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYK 940

  Fly  1015 RISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAE 1079
            ||:::|.|.||||:...:...:|..::|:|||.::....:.|:||:.|::|..::|:||:...::
plant   941 RIAQMICYFFYKNITFGLTLFYFECFTGFSGQSIYNDSYLLLFNVVLTSLPVISLGVFEQDVPSD 1005

  Fly  1080 TMIRYPMLYKTSQNAKLFNVKVFWI----WIFNALLHSVFLFWLPLAAYTKEVIWSDGKTSDYLL 1140
            ..:::|.||:.......|:    |.    |:.|.:..|:.:|.|.|..:..:...|||:|:|...
plant  1006 VCLQFPALYQQGPKNLFFD----WYRILGWMGNGVYASIVIFTLNLGIFHVQSFRSDGQTADMNA 1066

  Fly  1141 MGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLIYSHVWPMFKFASNFRGMDIQ 1205
            ||..::|.:|..|.::..|..:.:||:.|:.|||||..|:.||.:|. :.|: |.:.|...|.::
plant  1067 MGTAMFTCIIWAVNVQIALTMSHFTWIQHVMIWGSIGAWYVFLALYG-MLPV-KLSGNIFHMLVE 1129

  Fly  1206 LLS-TPVFYF-CLMLVPITTLLIDVICKLVHNTVFKTLT----EAVRETEIRRSDISEVMNEPRS 1264
            :|: .|:|:. .|:::..|||..     |.|.:..:::.    ..::|.:..|.|:.:.....|.
plant  1130 ILAPAPIFWLTSLLVIAATTLPY-----LFHISYQRSVNPLDHHIIQEIKHFRIDVEDERMWKRE 1189

  Fly  1265 SDS-------GFGYALGKLIRSSHILISHDHHPVSESSRTSN 1299
            ...       ||...:...||.....:...|..:|..|.||:
plant  1190 KSKAREKTKIGFTARVDAKIRQLRGRLQRKHSVLSVMSGTSS 1231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	P-type_ATPase_APLT_Dnf-like	231..1120	CDD:319770	401/995 (40%)
AT1G54280	NP_175830.1	Haloacid Dehalogenase-like Hydrolases	59..1172	CDD:473868	440/1130 (39%)