Protein Alignment ATP8A and atp8a1

DIOPT Version :9

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_031751247.1
• Gene: atp8a1 / 733571
• XenbaseID: XB-GENE-1000407
• Length: 1164
• Species: Xenopus tropicalis
• Alignment Length: 1099
• Identity: 619/1099 - (56%)
• Similarity: 800/1099 - (72%)
• Gaps: 24/1099 - (2%)

  Fly   183 LRMTASFLRRKRTEYEDDEDFTSSAGYDADDGERRIINLNGPQPTKYGNNRITTAKYSFISFLPA 247
            ::.|.|.:|.:...||..:|.:..... ||..|.|||.:|.||.||:.||.::||||:.|:|||.
 Frog     4 VQTTVSDMRTRAEGYEKTDDVSEKTSL-ADQEEMRIIFINQPQLTKFCNNHVSTAKYNPITFLPR 67

  Fly   248 FLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINH 312
            ||:.||||.:|.|||.||:|||||:|||||||||||||:|||:|:||||||||||||:|||.:|.
 Frog    68 FLYSQFRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLLFILTVAAIKEIIEDIKRHKADNFVNK 132

  Fly   313 RSIERLDSGSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIR 377
            :..:.|.:|:|..|.|.:..|||::|:....:.|||:||||||||||||:|||:|||||||||||
 Frog   133 KKTQVLRNGAWEIVHWEKTEVGDVVKIIGTEYIPADIILLSSSEPQAMCYIETSNLDGETNLKIR 197

  Fly   378 QALPATAELLETKDLQRLEGRIECELPNRHLYEFNGVLRETGKPPAALGNDQVLQRGAILRNTAW 442
            |.|..|||:.:...|..|.|:||||.||||||:|||.:|..|.....||.||:|.|||.||||.|
 Frog   198 QGLSVTAEMKDIDTLMSLSGKIECESPNRHLYDFNGNIRLDGHGLVPLGPDQILLRGAQLRNTQW 262

  Fly   443 VFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETD 507
            |.|||||:|.:||||:|||..|||.|.|:::||.|||:||..||::.::..:....|...|.:.|
 Frog   263 VHGIVVYTGHDTKLMQNSTRPPLKLSNVERITNIQILLLFGTLIAISLVCSIGCSIWNSRHGDKD 327

  Fly   508 WYLGLTDFKTKSLGYNLLTFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMAR 572
            |||.|......:.|.|.|||.||:||||||||.||||:|:|:||.|||:|::|.:|.::|.||||
 Frog   328 WYLSLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFIQAYFINWDVDMLYEPTDTAAMAR 392

  Fly   573 TSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYTAERTPEESQ---------------- 621
            |||||||||.|||||||||||||.|||:||||:|||..|.....|||.:
 Frog   393 TSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGNAYGHCPEPEEDRYSDDGWHYSHSEEGRD 457

  Fly   622 -----LVQNILGRHETSAVIEEFLELLSVCHTVIPERKENGNMIYHAASPDERALVEGAQKFGYI 681
                 |::|:...|.|:.||.|||.::::|||.:||| :...:||.|:||||.|||..|::..::
 Frog   458 FQDPSLMENLENNHPTAPVICEFLTMMAICHTAVPER-DGDQIIYQASSPDEGALVRAAKQLRFV 521

  Fly   682 FDTRTPKYVEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTPENKIKLFCKGADTVIYERLAPQG 746
            |..|||..|.|.:||..:|:|:|:||||||:|||||:|||....|::|:|||||||||:||| :.
 Frog   522 FTARTPNSVIIESLGQEERFELLHVLEFTSNRKRMSVIVRNSAGKLRLYCKGADTVIYDRLA-ET 585

  Fly   747 QAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENN 811
            ..::|.||:|||:||::||||||.|||.|:...|:||...:.:||.::|||..|||:...|||.|
 Frog   586 SKYKEITLKHLEQFATEGLRTLCFAVASIQDSAYEEWLDVYHRASTSVQNRALKLEECYELIEKN 650

  Fly   812 LRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIIILNEES 876
            |.|||||||||:|||.|||||.:|:.|.|.||:|||||||||||||:||:|::.:|.::::||:|
 Frog   651 LHLLGATAIEDKLQDNVPETIETLVKADIRIWILTGDKQETAINIGHSCKLLTKNMGLLVINEDS 715

  Fly   877 LDATREVIHRHYGEFKSSSAKDANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQ 941
            ||.||||:..|......:..|:.:.||:|||.:|||||:..:|..|.||.:.|:.||||||||:|
 Frog   716 LDTTREVLSHHCSTLGDALRKENDFALIIDGKSLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780

  Fly   942 KAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLL 1006
            |:||||||.:....:|||||||||||:|||.|:||:||||.||||||.:||||||||:||:.|||
 Frog   781 KSEVVEMVKKQVKVITLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLL 845

  Fly  1007 VHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGL 1071
            |||||||.|::|.|||.||||:.||:||:|||..:|:|||||||||.||||||:||||||..:|:
 Frog   846 VHGAWNYNRVAKCILYCFYKNIVLYIIEIWFAFMNGFSGQILFERWCIGLYNVMFTAMPPLTLGI 910

  Fly  1072 FEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSDGKTS 1136
            ||:.|..|.|::||.||||||.|..||.||||:...|.|||||.|||.||.|...:.|:.:||||
 Frog   911 FERSCHKENMLKYPELYKTSQKALDFNTKVFWVHCLNGLLHSVILFWFPLKALQHDTIFGNGKTS 975

  Fly  1137 DYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLIYSHVWPMFKFASNFRG 1201
            ||||:||:|||:|::||||||||.|:.||..:|:||||||:||..|..|||.:||....|.:..|
 Frog   976 DYLLLGNIVYTFVVITVCLKAGLETSHWTKFSHIAIWGSILLWIVFFGIYSSLWPAIPLAPDMSG 1040

  Fly  1202 MDIQLLSTPVFYFCLMLVPITTLLIDVICKLVHNTVFKTLTEAVRETEIRRSDISEVMN 1260
            ....:.|:.||:..|..:|:|:||:||:.|.|..|.||||.:.|.|.|.:..|...|::
 Frog  1041 EADMMFSSGVFWMGLFFIPVTSLLLDVLYKAVQRTCFKTLVDEVHELEAKAQDPGAVVH 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	40/61 (66%)
		ATPase-Plipid	229..1247	CDD:273734	598/1038 (58%)
		E1-E2_ATPase	286..>371	CDD:278548	50/84 (60%)
		Cation_ATPase	645..741	CDD:289987	53/95 (56%)
		HAD_like	<942..1001	CDD:304363	42/58 (72%)
		PhoLip_ATPase_C	988..1240	CDD:292829	149/251 (59%)
atp8a1	XP_031751247.1	ATPase-Plipid	49..1086	CDD:273734	598/1038 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	326	1.000	Domainoid score	I1188
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H48402
Inparanoid	1	1.050	1240	1.000	Inparanoid score	I179
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	1	1.000	-	-		otm47813
Panther	1	1.100	-	-	O	PTHR24092
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160