Protein Alignment ATP8A and atp10d

DIOPT Version :9

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_012818017.1
• Gene: atp10d / 549378
• XenbaseID: XB-GENE-1000388
• Length: 1373
• Species: Xenopus tropicalis
• Alignment Length: 1425
• Identity: 426/1425 - (29%)
• Similarity: 650/1425 - (45%)
• Gaps: 359/1425 - (25%)

  Fly   193 KRTEYEDDEDFTSSAGYDADDG-------ERRIINLNG------PQPTK-YGNNRITTAKYSFIS 243
            :..:.||........|::..:|       .|.:|...|      .:.|| |.||||.|.||:.::
 Frog    21 RNRDLEDSSTSRKLLGFNKSNGTSSNSTKHRVVIPCLGQFKEEYEKLTKAYKNNRIQTTKYTLLN 85

  Fly   244 FLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADN 308
            |:|..|||||.|.:|.:||.:..|..:|.|....:..|::||:.:|::.|||:.:||.::::.|.
 Frog    86 FIPRNLFEQFHRAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDK 150

  Fly   309 EINHRSIERLDSGSWCTVR-------WSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETA 366
            .||:     :.:..:|...       |.::.||..|::..:...|||::||.||:|..:|.|||:
 Frog   151 VINN-----IVTQVYCRKEKKYKESCWKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETS 210

  Fly   367 NLDGETNLKIRQALPATAELLETKDLQRLEGRIECELPNRHLYEFNGVLRETGKPPAALGNDQVL 431
            :||||||||.||.:...: :.:..|.::..|||:||.|...:..|.|.|....|....|....:|
 Frog   211 SLDGETNLKQRQVVKGYS-MDDEFDPEKFSGRIQCENPTSDISSFKGFLDHPNKEKIGLSKQNLL 274

  Fly   432 QRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCN 496
            .||.|:|||..|.|||||:|.|||.|.|::....|||.:::..||.||...::||::|:...:.:
 Frog   275 LRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGH 339

  Fly   497 LFWTREHSETDWYL-----------GLTDFKTKSLGYNLLTFFILYNNLIPISLQVTLELVRFLQ 550
            ..|.....|:..:.           .|..|      |...|..||...||||||.|::|:|:..|
 Frog   340 GLWLAGFPESPIFSIPEPGGQHTSPALAGF------YMFWTMIILLQVLIPISLYVSIEIVKLGQ 398

  Fly   551 AIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYTAE- 614
            ..||..|.|.|.|:|::....|..|:.|:||.|:|||||||||||:|.|.|::|||||..|:.|
 Frog   399 IYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEA 463

  Fly   615 ----------------------------------------------------------------- 614
                                                                             
 Frog   464 NARRLESYQESDMHGSNLCHVTCISQSSVCKSKEQRKAASNKSLNNFAQGEDNDGASHPPNPRHV 528

  Fly   615 --RTPEESQLVQN--ILGRH-------------------ETSAVIEEFLELLSVCHTVI------ 650
              .:|.|..:|.:  :|.:.                   |||.:::.|| .|::|:||:
 Frog   529 AFSSPMEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETSYIVDFFL-ALAICNTVVVSLPNQ 592

  Fly   651 PERK------------------------------------------ENGN--------------- 658
            |.:|                                          |||:
 Frog   593 PRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSNFGSKLSFFTRGKLA 657

  Fly   659 --------------------------------------------------MIYHAASPDERALVE 673
                                                              :.|.|.||||.|||.
 Frog   658 SPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVH 722

  Fly   674 GAQKFGYIFDTRTPKY--VEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTP-ENKIKLFCKGAD 735
            .|:.:.....:|||..  ||:..:| ...::||::|.|.|.|||||:|:|.| .||:.::.||||
 Frog   723 AARAYNCTLQSRTPDQVTVELGFIG-PLTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGAD 786

  Fly   736 TVIYERLAPQGQ---------AFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKAS 791
            :.|.:.:|...:         ..:..|.:||:::|..||||||:|...:....|.||.|:...|.
 Frog   787 SAIMDLIAMTSEDNKAAMVKKNIQMLTQKHLDDYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAE 851

  Fly   792 VALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINI 856
            .::.|||..|.::|..:|..|.|||||.||||||:|||:||.||..|||.||:|||||:|||:||
 Frog   852 TSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNI 916

  Fly   857 GYSCRLISHSMDIIILNEESLDATREVIHRHYGEFKSSSAKDA-----------NVALVIDGTTL 910
            .|:|||:.||..:..|::...::...:::....|..|....:|           :..|||||.||
 Frog   917 AYACRLLEHSDKLFNLSKHEKESCETLMNIMIDEIDSLGKPNAFSSGQQDKSGLHFGLVIDGGTL 981

  Fly   911 KYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANV 975
            :.|:...|::.|..|...||.|||||.:|:||::||::|..:...:.||||||||||:|||.|::
 Frog   982 EIAMHESLQSKFLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADI 1046

  Fly   976 GIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVY 1040
            |:||||.||:||..:||::::.|::|::||||||.|.|.|::.:|||.||||:....:..|:..:
 Frog  1047 GVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFF 1111

  Fly  1041 SGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIW 1105
            .|:||..:.:.|.:.|:|:|||::||...|:.:|..:|||:...|.|||:.|.::.:....||:.
 Frog  1112 CGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVT 1176

  Fly  1106 IFNALLHSVFLFWLPLAAYTKEVIWSDGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHL 1170
            |.:|...|:..|::|..||.       |........||.:.|..:..|.|...:.:.|.||:..:
 Frog  1177 ILDAFYQSLACFFIPYFAYI-------GSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWI 1234

  Fly  1171 AIWGSIVLWFGFLLIYSHVW--------PMFKFASNFRGMDIQLLSTPVFYFCLMLVPITTLLID 1227
            .:..||..:|.|.|.:..|.        |.:...::.|        .|.||...:|.....||..
 Frog  1235 VMGASIAAYFAFSLAFGAVCINCNPPANPYWIVQNHVR--------DPAFYLVCLLSIFIALLPR 1291

  Fly  1228 VICKLVHNTVFKTLTEAVRETEIRRSDISEVMNEPRSSDSGFGYALGKLIRSSHILISHDHHPVS 1292
            .:|::...|||.
 Frog  1292 YVCRIFQGTVFP----------------------------------------------------- 1303

  Fly  1293 ESSRTSNLRVENLEMEADTEQQQQSRQRQKWRGGQVATGVARS-----ARNSTTSPITAT 1347
                |..|..:.|::   ...:::||..::|||||...|...|     |..|.|:...||
 Frog  1304 ----TPQLLAKKLDV---MSPEERSRALKRWRGGQSLKGRKASQHLEPAGGSVTTKEEAT 1356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	26/68 (38%)
		ATPase-Plipid	229..1247	CDD:273734	400/1268 (32%)
		E1-E2_ATPase	286..>371	CDD:278548	28/91 (31%)
		Cation_ATPase	645..741	CDD:289987	44/211 (21%)
		HAD_like	<942..1001	CDD:304363	30/58 (52%)
		PhoLip_ATPase_C	988..1240	CDD:292829	78/259 (30%)
atp10d	XP_012818017.1	P-type_ATPase_APLT_Dnf-like	73..1191	CDD:319770	369/1131 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010