Protein Alignment ATP8A and LOC1277786

DIOPT Version :10

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_061518483.1
• Gene: LOC1277786 / 1277786
• VectorBaseID: AGAMI1_003457
• Length: 1155
• Species: Anopheles gambiae
• Alignment Length: 1105
• Identity: 318/1105 - (28%)
• Similarity: 508/1105 - (45%)
• Gaps: 189/1105 - (17%)

  Fly   217 RIINLNGPQPTKYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTT 281
            |.|.:..|...|:..|.|...||:|.:|||..||||||.:.|.:||::|:.|.|||:.....||.
Mosquito    71 RTIYIGRPLTEKFPPNEIRNQKYNFFTFLPLVLFEQFRFFLNLYFLIMAVSQFIPEIRIGYLYTY 135

  Fly   282 LVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDSGSWC--TVRWSELTVGDIIKVGINTF 344
            ..||.|:|:|:..:|.::|::||:.|.|:|.:..:|..|....  :|..|:|.|||||.|..:..
Mosquito   136 WGPLGFVLAVTICREAVDDLRRHKRDREVNSQKYKRFVSADKPPESVSSSKLRVGDIIMVEKDER 200

  Fly   345 FPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRIECELPNRHLY 409
            .|||||||.:|:.....|:.|..|||||:.|:|.|:|||.:|....:|..:...:..|.|.|.::
Mosquito   201 VPADLILLRTSDKSGAVFVRTDMLDGETDWKLRLAVPATQKLASHGELLTVNASLYVEKPQRDIH 265

  Fly   410 EFNGVLRETGKPPAALGNDQVLQRGAILRNTAW---------VFGIVVYSGQETKLMKNSTSAPL 465
            .|.|...:.|      |.:   ..|..:.||.|         ..|||:|:|.||:.:.|::....
Mosquito   266 TFIGTYSKHG------GTE---DEGLNVENTLWANTVVASGTAVGIVIYTGSETRSVMNNSQPRS 321

  Fly   466 KRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLTDFKTKSLGYNLLTFFIL 530
            |...:|...|....:||      |.:.||.......:.....||            ..:..|.:|
Mosquito   322 KVGLLDLEINNLTKVLF------CAVIGLSFAMMCLKGFNGPWY------------RYMFRFVLL 368

  Fly   531 YNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLT 595
            ::.:|||||:|.|::.:    .|.::.|:...|...|  :.|::.:.||||.:.|:.:|||||||
Mosquito   369 FSYIIPISLRVNLDMGK----AFYSWQIQNDDEIKGT--VVRSTTIPEELGRMSYLLTDKTGTLT 427

  Fly   596 QNVMEFKKCSIAGYVYTAERTPEESQLVQNILG---------------------RHETSAVIEEF 639
            ||.|.|||..:....|..:..|..|..:|::.|                     |......|.|.
Mosquito   428 QNEMIFKKIHVGTAAYGRDTFPMVSAAIQSVYGTLSAPADASPEDHGSEYQPRLRKPDGWRIWES 492

  Fly   640 LELLSVCHTVIP-ERKENGN--------------------------------------MIYHAAS 665
            ::.|::||.|.| ....|||                                      ..|.|:|
Mosquito   493 VKALALCHNVTPVYESNNGNGGSGSISSTSDRRQSPARSISVESQAGEPSTSKPATTEKTYQASS 557

  Fly   666 PDERALVEGAQKFGYIF-------------------------------------------DTRTP 687
            |||.|||:..:..|...                                           |..:|
Mosquito   558 PDEIALVKWTESVGLTLVQRDLNHMTLQIRDATHEARGTSMNENASINTTVTNLSVNSKTDLNSP 622

  Fly   688 ----------KYVEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTPE-NKIKLFCKGADTVIYER 741
                      ..:...|.|:.| |::|....|||..|||.:|||... .:|..:.|||| |:...
Mosquito   623 SSGGSVTSLNSIIAAGAPGLMK-YQILQTFPFTSENKRMGIIVRELNGGEITFYLKGAD-VVMSG 685

  Fly   742 LAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAAN 806
            :........|::    ...|.:|||||.:|...:..:.|.::...::.|.|::.:|.:|:.....
Mosquito   686 IVQYNDWLAEES----GNMAREGLRTLVVAKKVLSEEQYNDFVMRYNAAKVSVTDRVAKVAAVIE 746

  Fly   807 LIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIII 871
            .:|..:.||..|.:||||||.|..|:..|.:|||.||:|||||.|||..|..|..|:..:..|.:
Mosquito   747 SLEREMELLCLTGVEDRLQDRVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVGRNQSIHV 811

  Fly   872 LNEESLDATREVIHRHYGEFKSSSAKDANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCR 936
            |...   .||...|....:|:    :..:.|||:.|.:|:..|.. .:.:|.:|...|..|:|||
Mosquito   812 LKSV---LTRTDAHLELNQFR----RKQDCALVVSGESLEVCLQY-YQPEFMELATACPAVVCCR 868

  Fly   937 VSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYL 1001
            .||.|||:||.::.:.:...|.|:|||.|||:|||:|:.||||.|.||.||:.|.|:||.||.::
Mosquito   869 CSPTQKAQVVSLIQKYSKKRTCAVGDGGNDVSMIQQADAGIGIEGREGKQASLAGDFSIPQFSHI 933

  Fly  1002 QRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPP 1066
            .|||:|||..:|.|.:.|..:..::.:.:..::..|:.....|...|::.:.:..|..|:|..|.
Mosquito   934 ARLLIVHGRRSYKRSAALSQFVIHRGLIISTMQAVFSAVFYLSSVALYQGFLMVGYATLYTMFPV 998

  Fly  1067 FAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWS 1131
            |:: :.::..:|...|.||.|||.....:..:.|.|::|:.      :.::...:..|...:::.
Mosquito   999 FSL-VLDQDISANIAITYPELYKELSKGRSLSYKTFFMWVL------ISIYQGGVIMYGALILFE 1056

  Fly  1132 DGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLI------YSHVW 1190
            |    :::.:..:.::.:|:|..:...|...:|..|..:|...|:||:...|.:      :..:|
Mosquito  1057 D----EFIHIVAISFSALILTELIMVALTIRTWHKLMVIAELFSLVLYIVSLAVLHEYFDWEFIW 1117

  Fly  1191  1190
            Mosquito  1118  1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	P-type_ATPase_APLT_Dnf-like	231..1120	CDD:319770	301/1013 (30%)
LOC1277786	XP_061518483.1	None