Protein Alignment ATP8A and atp9b

DIOPT Version :9

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_002936489.3
• Gene: atp9b / 100497381
• XenbaseID: XB-GENE-1012387
• Length: 1256
• Species: Xenopus tropicalis
• Alignment Length: 1220
• Identity: 327/1220 - (26%)
• Similarity: 543/1220 - (44%)
• Gaps: 217/1220 - (17%)

  Fly   137 PPASVSTSVGGTLSSRRRSSNRKDSKGSILSRQSGKSRVSL--LAQRGLRMTASFLRRKRTEYED 199
            |.|..|..|.|.|...           |::.|:.....:.|  :.:|....||...:| |.:.||
 Frog   101 PEAKSSAIVAGCLPVT-----------SVVERRKMADSIPLQPVQKRAAYYTADRSKR-RYQLED 153

  Fly   200 DED-------FTSSAGYDADDGE----------RR----------------------IIN----- 220
            :..       ..|..|::.|:.:          ||                      :||
 Frog   154 EASPLDEMPLMMSEEGFENDESDYQTLPRARITRRKKGLEWFLCGGWKFLCTSCCEWLINVCRRK 218

  Fly   221 ---------LNGPQ--PTKYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVS 274
                     |..|:  ..||..|.|...||:..:|:|..|::||:.:.|.:||::|..|.:..:.
 Frog   219 KELKARTVWLGCPEKCEEKYPRNAIKNQKYNIFTFIPGVLYQQFKFFLNLYFLVVACSQFVSALK 283

  Fly   275 PTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRSIERLDSGSWCTVRWSELTVGDIIKV 339
            ....||...||.|:|:|:.::|..::.:|.:.|.|:|.:...:|.......|:.|::.|||:|.|
 Frog   284 IGYLYTYWAPLGFVLAVTMVREAADEYRRFQRDKEMNSQLYSKLTIRGKVQVKSSDIQVGDLIIV 348

  Fly   340 GINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLEGRIECELP 404
            ..|...|||::.|.:||....|||.|..|||||:.|::.|:..|..|....||..:...:..:.|
 Frog   349 EKNQRIPADMVFLRTSEKTGSCFIRTDQLDGETDWKLKIAVSCTQRLPALGDLFSINAYVYAQKP 413

  Fly   405 NRHLYEFNGVLRETGKPPAALGNDQVLQRGAILRNTAW---------VFGIVVYSGQETKLMKNS 460
            ...::.|.|........|:       :.....:.||.|         |.|:|:|:|:||:.:.|:
 Frog   414 QLDIHSFEGNFTREDTDPS-------IHESLSIENTLWASTVVASGTVIGVVIYTGKETRSVMNT 471

  Fly   461 TSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDWYLGLTDFKTKSLGYNLL 525
            ::...|...:|...|.....||:.|::|.::      ..|.:.....||            ..|.
 Frog   472 SNPKNKVGMLDLELNQLTKALFLALVALSVV------MVTLQGFVGPWY------------RYLF 518

  Fly   526 TFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTP-AMARTSNLNEELGMVKYIFSD 589
            .|.:|::.:|||||:|.|::.:......|..|       .|.| .:.|||.:.||||.:.|:.:|
 Frog   519 RFLLLFSYIIPISLRVNLDMGKAAYGWMIMRD-------ENIPGTVVRTSTIPEELGRLVYLLTD 576

  Fly   590 KTGTLTQNVMEFKKCSIAGYVYTAERTPEESQLVQNILG-------------------------- 628
            ||||||||.|.||:..:....|..:...|    :||.:.
 Frog   577 KTGTLTQNEMVFKRLHLGTVSYGTDTMDE----IQNHIASSYSLVQPSQSCNNNTSATPSRKGQS 637

  Fly   629 -----RHETSAVIEEFLELLSVCHTVIPERKE----NG--------------NMIYHAASPDERA 670
                 |...|:.:.|.::.:::||.|.|..:.    ||              |..|.|:||||.|
 Frog   638 SAPKVRKTVSSRVHEAVKAIALCHNVTPVYESRAGVNGETEYSEVDQDFCDENRTYQASSPDEVA 702

  Fly   671 LVEGAQKFGYIFDTRTPKYVEINALGVR-KRYEVLNVLEFTSSRKRMSLIVRTPEN-KIKLFCKG 733
            ||:..:..|.....|....:::...|.: ..:.:|.:..|||..|||.:|||...: .|..:.||
 Frog   703 LVQWTESVGLTLVNRDLTSMQLKTPGGQILTFCILQIFPFTSESKRMGIIVREESSGDITFYMKG 767

  Fly   734 AD----TVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVAL 794
            ||    |::         .:.:.........|.:|||||.:|...:..:.||::...:::|.:::
 Frog   768 ADVAMATIV---------QYNDWLDEECGNMAREGLRTLVVAKKSLSEEQYQDFENRYNQAKLSM 823

  Fly   795 QNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYS 859
            .:|..|:......:|..:.||..|.:||:||..|..|:..|.:|||.||:|||||.|||..|..|
 Frog   824 HDRALKVAAVVESLEREMELLCLTGVEDQLQTDVRPTLEMLRNAGIKIWMLTGDKLETATCIAKS 888

  Fly   860 CRLISHSMDIIILNEESLDATREVIHRHYGEFKSSSAKDANVALVIDGTTLKYALSCDLRNDFQD 924
            ..|:|.:.||.|....|   .|...|.....|:    :..:.||||.|.:|:..|.. ..::|.:
 Frog   889 SHLVSRNQDIHIFRPVS---NRSEAHLELNAFR----RKHDCALVIAGDSLEVCLKY-YEHEFVE 945

  Fly   925 LCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAAC 989
            |...|..|:|||.||.|||.:|:::.|.|...|.|||||.|||:|||.|:.||||.|.||.||:.
 Frog   946 LACQCPAVVCCRCSPTQKAHIVKLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASL 1010

  Fly   990 ASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTI 1054
            |:|:||.||:::.|||:|||..:|.|.:.|..:..::.:.:..::..|:....::...|::.:.:
 Frog  1011 AADFSITQFKHIGRLLMVHGRNSYKRSAALGQFVIHRGLVISTMQAVFSSVFYFASVPLYQGFLM 1075

  Fly  1055 GLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWL 1119
            ..|..::|..|.|:: :.::....||.:.||.|||.....:..:.|.|.||:..::.....|.:.
 Frog  1076 VGYATIYTMFPVFSL-VLDQDVKPETALLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMFG 1139

  Fly  1120 PLAAYTKEVIWSDGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLL 1184
            .|..:          .|:::.:..:.:|.:|:|..|...|...:|.||..:|...|:..:...|
 Frog  1140 ALVLF----------ESEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAELFSLASYVASL- 1193

  Fly  1185 IYSHVWPMFKFASNFRG---------MDIQLLSTPVFYFCLMLVPITTLL 1225
                     .|.:.:.|         :|...::|..|.:.::.:.:.:.|
 Frog  1194 ---------AFLNEYFGLGRVSLGAFLDAAFITTLTFLWKVLAITVVSCL 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	20/77 (26%)
		ATPase-Plipid	229..1247	CDD:273734	301/1071 (28%)
		E1-E2_ATPase	286..>371	CDD:278548	29/84 (35%)
		Cation_ATPase	645..741	CDD:289987	35/119 (29%)
		HAD_like	<942..1001	CDD:304363	33/58 (57%)
		PhoLip_ATPase_C	988..1240	CDD:292829	52/247 (21%)
atp9b	XP_002936489.3	P-type_ATPase_APLT_Neo1-like	240..1165	CDD:319841	286/988 (29%)
		Cation_ATPase	658..769	CDD:404183	32/110 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930