Protein Alignment ATP8A and atp8b3

DIOPT Version :9

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_031760429.1
• Gene: atp8b3 / 100490666
• XenbaseID: XB-GENE-992174
• Length: 1181
• Species: Xenopus tropicalis
• Alignment Length: 1188
• Identity: 447/1188 - (37%)
• Similarity: 665/1188 - (55%)
• Gaps: 120/1188 - (10%)

  Fly   190 LRRKRTEYEDDEDFTSSAGYD----ADDGERRIINLNGPQPT-------KYGNNRITTAKYSFIS 243
            :.:|:::.|||.::...:.|.    |:|   ||.|.:..:.|       ||.:|.|||:||:.::
 Frog     1 MNQKQSQDEDDSEYEGKSKYTWEVRAND---RIFNSSVKKKTWLFFKKKKYASNSITTSKYNILT 62

  Fly   244 FLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADN 308
            |:|..|||||.|.:|.:||.|.|||.||.:|....:..::||:|:|.:..|:::|:||.|||:|.
 Frog    63 FIPLSLFEQFHRMANLYFLFIIILQTIPAISTLPWFAIMLPLLFLLVIRGIRDLIDDIVRHRSDK 127

  Fly   309 EINHRSIERLDSGSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETN 373
            .||:|..|.|...|:|..:|.::..|||:::..|.:.||||.||.||||.::|::|||::|||||
 Frog   128 AINNRPCEILKGQSFCMEKWKDIQTGDIVRIQKNDYVPADLFLLKSSEPSSLCYVETADIDGETN 192

  Fly   374 LKIRQALPATAELLETKD-LQRLEGRIECELPNRHLYEFNGVLRETG-KPPAALGNDQVLQRGAI 436
            ||.:|||..|.:.|.|:: |....|::.||.||.:::.|.|.|...| |.|  |.||.:|.||..
 Frog   193 LKFKQALMVTHQGLSTEESLSNFVGKVICEEPNSNMHTFIGTLEWNGEKYP--LDNDCILLRGCR 255

  Fly   437 LRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILI----SLCIISGLCNL 497
            :|||...:|:|:|:|.:||:|:|.....:|::.::|:.|..::::|.:||    .|.||:|..:.
 Frog   256 IRNTETCYGLVIYAGFDTKIMRNGGKVRVKKTKLEKMMNILVIIIFGMLIICAAVLAIIAGYRSA 320

  Fly   498 FWTREHS--------ETDWYLGLTDFKTKSLGYNLLTFFILYNNLIPISLQVTLELVRFLQAIFI 554
            ::..:||        :|..|.....|    .||     .||.:.::|:|:.:||||:..:..:||
 Frog   321 WFKGKHSYIPPLAENDTPAYTAFLVF----WGY-----VILLSTIVPMSMYITLELIHLIHNMFI 376

  Fly   555 NYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYTAERTPEE 619
            |:|.:||..:.||.|.||:|:||:.||.|:|:|||||||||||:|.||||.|.|..|......||
 Frog   377 NWDEDMYSTKKNTAANARSSSLNDVLGQVEYVFSDKTGTLTQNIMTFKKCCINGKTYGKSSKDEE 441

  Fly   620 SQLV-----------------QNILGR--HETSAVIEEFLELLSVCHTVIPERKENGNMIYHAAS 665
            :..|                 |::|..  .....|..||..:|::||||:.|| ..|.:||.|||
 Frog   442 NNEVVNFSWNKYADKNFQFYDQSLLDMVCENKDGVYREFFRVLALCHTVMVER-NGGEIIYKAAS 505

  Fly   666 PDERALVEGAQKFGYIFDTRTPKYVEINALGVRKRYEVLNVLEFTSSRKRMSLIVRTPENKIKLF 730
            |||.|||..|:..||:|.:||...:.:|.||..:.|.||..|:|:|.|||||::|:.|:.||||:
 Frog   506 PDEEALVTAARNVGYVFLSRTQDTMTVNELGEERTYRVLAFLDFSSVRKRMSILVKDPDGKIKLY 570

  Fly   731 CKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQ 795
            .||||.||..||..:..:: |.|.:.|..||.|.|||||:|..|:...||..||:.:.:|||.||
 Frog   571 TKGADDVILRRLHSECSSY-EITEKALAMFAHDTLRTLCVACKDVDIPVYTAWSKRYHQASVTLQ 634

  Fly   796 NRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSC 860
            ||.:.||...:.:|.:|:|||||||||:|||.|||||..|.|..:.:|||||||||||||||:||
 Frog   635 NRTALLERVYDELETDLQLLGATAIEDKLQDKVPETIQLLKDGNMKVWVLTGDKQETAINIGFSC 699

  Fly   861 RLISHSMDIIILNEESLDATREVIHRHYGEFKSS---------------SAKDANVALVIDGTTL 910
            ||:|..|:  ||:||.:....:....|......|               |.:...:|||:.|..|
 Frog   700 RLLSDDME--ILDEEQISDILDEYWEHNNNVSGSGQDLVGSNSFKKHRASLQGRKMALVVSGDFL 762

  Fly   911 KYALSCDL----------------RND-----------FQDLCILCRVVICCRVSPMQKAEVVEM 948
            ...|...:                ||.           |.||...|:.||||||:|.||:.||::
 Frog   763 DRILGTKIQKQGKLLLLRKCFNWKRNQNKQEDSLKEWAFVDLASQCQTVICCRVTPKQKSMVVQL 827

  Fly   949 VTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNY 1013
            |.:...|.|||||||||||.||:.|::|:||||:||.||..:||:|||||.:|||||.:||.|:|
 Frog   828 VKKHKRATTLAIGDGANDVNMIKTADIGVGISGLEGTQAVQSSDFSIAQFCFLQRLLFIHGRWSY 892

  Fly  1014 ARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTA 1078
            .||:|...|.|||.....:..:||..::|::...|::.|.|.||.::||:.|..::.:.|:..||
 Frog   893 LRITKFFKYFFYKTFANVLGHVWFGFFNGFTALTLYDSWYISLYAIMFTSFPVLSLAVLEQDVTA 957

  Fly  1079 ETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSDGKTSDYLLMGN 1143
            |..:..|.||:..|:..||..|.|.......:..|:..|::....: ::.....| ..||.....
 Frog   958 EISLLSPELYRVGQSGSLFTYKTFLGSFLKGIATSLSSFFISFGTF-QDTAGPSG-ICDYQAFAV 1020

  Fly  1144 LVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWFGFLLIYSHVWPMFKFAS---NFRGMDIQ 1205
            ...|.||::|.|:.....:.||.|:.:|:..|.:|:| .....|..:|:|.|..   .|.|:...
 Frog  1021 TTATTVILSVTLEITFEISYWTRLSVIAVVISPLLYF-LSSFTSQAFPLFVFLPTMFQFPGVSRN 1084

  Fly  1206 LLSTPVFYFCLMLVPITTLLIDVICKLVHNTVFKTLTEAVRETEIRRSDISEVMNEPRSSDSGFG 1270
            .||....:.        |:::.|:..::.:.|....|:.:...:|..:..|:......|::...|
 Frog  1085 ALSHGYIWL--------TIILGVVISILPSLVMIFCTKLMSRNQIHSNMGSKADTTSASNEIALG 1141

  Fly  1271 --YALGKLIRSSHILISH 1286
              :..|.:.|.|....||
 Frog  1142 TPFKKGTVHRRSSYAFSH 1159

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	29/68 (43%)
		ATPase-Plipid	229..1247	CDD:273734	426/1095 (39%)
		E1-E2_ATPase	286..>371	CDD:278548	37/84 (44%)
		Cation_ATPase	645..741	CDD:289987	50/95 (53%)
		HAD_like	<942..1001	CDD:304363	35/58 (60%)
		PhoLip_ATPase_C	988..1240	CDD:292829	74/254 (29%)
atp8b3	XP_031760429.1	P-type_ATPase_APLT_Dnf-like	50..999	CDD:319770	398/963 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930