Protein Alignment ATP8A and XB994119

DIOPT Version :9

• Sequence 1: NP_001137651.1
• Gene: ATP8A / 36488
• FlyBaseID: FBgn0259221
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: XP_002940236.3
• Gene: XB994119 / 100490503
• XenbaseID: XB-GENE-994120
• Length: 1179
• Species: Xenopus tropicalis
• Alignment Length: 1141
• Identity: 449/1141 - (39%)
• Similarity: 671/1141 - (58%)
• Gaps: 110/1141 - (9%)

  Fly   228 KYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVS 292
            ||..|.|.|.||:..:|||..|||||:|.:|.:|:.:.|||.||:||....:||:|||:.:|:||
 Frog    32 KYATNAIKTCKYNIFTFLPLNLFEQFQRVANAYFVFLLILQLIPQVSSLSWFTTVVPLVLVLAVS 96

  Fly   293 AIKEIIEDIKRHRADNEINHRSIERLDSGSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEP 357
            |:|:..:|..||::||::|:|:::.|.:|.:...:|..:.||||||:..|.|..|||:|||||||
 Frog    97 AVKDATDDYYRHKSDNQVNNRTVQVLSNGQFTNEKWMNIQVGDIIKLENNNFVTADLLLLSSSEP 161

  Fly   358 QAMCFIETANLDGETNLKIRQALPATAELLE-TKDLQRLEGRIECELPNRHLYEFNGVLRETGKP 421
            ..:.:||||.||||||||::|:|..|.:|.| .:.|.|.:|.:.||.||..|..|.|.|...|:
 Frog   162 NGLIYIETAELDGETNLKVKQSLTVTGDLGEDLEQLSRFDGEVVCEAPNNKLDTFTGTLTYQGE- 225

  Fly   422 PAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILI 486
            ..:|.|.::|.||..||||.|.||:|:::|.:||||:||..:.|||:::|:|.|..:|.:|:.|.
 Frog   226 KYSLDNGKILLRGCTLRNTDWCFGMVIFAGPDTKLMQNSGKSTLKRTSIDRLMNILVLWIFVFLA 290

  Fly   487 SLCIISGLCNLFWTREHS-----ETDWYLGLTDFKTKSLGYNLL-TFFILYNNLIPISLQVTLEL 545
            ::|||..:.|..|.....     ...|..|:|:  ....|:.:. ::.|:.|.::||||.|::|:
 Frog   291 AMCIILAIGNGIWESNQGYYFQVYLPWAEGVTN--AAFSGFLMFWSYVIILNTVVPISLYVSVEI 353

  Fly   546 VRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAG-- 608
            :|...:.:||:|.:||:.:.:|||.|||:.||||||.:||||||||||||||:|.|.||||.|
 Frog   354 IRLGNSYYINWDRKMYYPKKDTPAEARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNKCSINGNS 418

  Fly   609 ----YVYTAERTP----------------------EESQLVQNI-LGRHETSAVIEEFLELLSVC 646
                |.|...|..                      .:.:||::: ||...|    .||..||::|
 Frog   419 YGDVYDYAGNRLEINEHTEKVDFSFNPLADPKFSFHDHRLVESVKLGEPAT----HEFFRLLALC 479

  Fly   647 HTVIPERKENGNMIYHAASPDERALVEGAQKFGYIFDTRTPKYVEINALGVRKRYEVLNVLEFTS 711
            ||.:.|.|:.|.::|.|.||||.|||..|:.||::|.||||:.:.:..:|..|.||:..:|:|.:
 Frog   480 HTAMSEEKKPGELVYQAQSPDEGALVTAARNFGFVFRTRTPETITVVEMGETKVYELQAILDFNN 544

  Fly   712 SRKRMSLIVRTPENKIKLFCKGADTVIYERLAPQGQAFREQTLRHLEEFASDGLRTLCLAVADIR 776
            .|||||:||::|:.::.|:||||||::||.|....:..:|.|..||.|||.:|||||.||..::.
 Frog   545 ERKRMSVIVKSPDGRLILYCKGADTIVYELLDQSSEDLKETTTEHLNEFAGEGLRTLVLACKELN 609

  Fly   777 PDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIY 841
            |..:::|.|...:||.:|.:||.||......||.:|:||||:||||:||||||:||.:|..|.|.
 Frog   610 PTYFRDWKQRHHEASTSLDDREEKLAKLYEEIEKDLKLLGASAIEDKLQDGVPQTIETLSKANIK 674

  Fly   842 IWVLTGDKQETAINIGYSCRLISHSM-DIII-------------------LNEESLDATREV-IH 885
            ||||||||||||.||||||.::...| ::.|                   :|.||...|.|| ::
 Frog   675 IWVLTGDKQETAENIGYSCNMLQDEMKEVFIIKGCSPDEVLEELRSARRKMNPESFSETNEVNVY 739

  Fly   886 RHYGEFKSSSAKDANV------ALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAE 944
            ......||....|..:      .::|:|.:|.:||...:..:......:|..||||||:|:|||:
 Frog   740 LQKKSKKSQIIPDDELKGSDTFGILINGHSLAFALEESMEIELLRTACMCTAVICCRVTPLQKAQ 804

  Fly   945 VVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHG 1009
            ||::|.:...|||||||||||||:||:.|::|:||||.||:||..:||:|.||||||||||||||
 Frog   805 VVQLVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLSSDFSFAQFRYLQRLLLVHG 869

  Fly  1010 AWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEK 1074
            .|:|.|:.:.:.|.||||....::..|:..:.|:|.|.:::.|.|.|||:::|::|...|.||::
 Frog   870 RWSYIRMCRFLRYFFYKNFTFTLVHFWYGFFCGFSAQTVYDEWFITLYNLVYTSLPVLGMSLFDQ 934

  Fly  1075 FCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSDGKT-SDY 1138
            .......:::|.||:..|..:.||:|.|...:.:.:..|:.||::|..| ..|.:..||:. |||
 Frog   935 DVNDRWSLQFPELYEPGQMNRYFNIKEFIKCVLHGIYSSLILFFIPFGA-MYESVREDGRAISDY 998

  Fly  1139 LLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVLWF---------GFLLIYSHVWPMFK 1194
            .....:..|.:::.|.::.||.|..||.:....||||:.::|         |..||::..:|...
 Frog   999 QSFALMAQTCLLLVVSVQIGLDTAYWTAVNQFFIWGSMAVYFAITFTMYSDGMYLIFTGSFPFIG 1063

  Fly  1195 FASNFRGMDIQLLSTPVFYFCLMLVPITTLLIDVICKLVHNTVFKTLTEAVRETEIRRSDISEVM 1259
            .|.|       .|:.|..:..:.|..:..:|..|..:.:.:.:|.:..:.:::      .|.|..
 Frog  1064 TARN-------TLNQPGVWLAIFLTTVLCVLPVVAFRFLRSELFPSTGDKIQK------KIREAK 1115

  Fly  1260 NEP----------RSSDSGFGYAL------GKLIRS 1279
            ..|          |:|....|||.      |.||.|
 Frog  1116 KRPPPPPPKARLRRTSSRRSGYAFSHQQGYGDLITS 1151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8A	NP_001137651.1	PhoLip_ATPase_N	218..280	CDD:292826	25/51 (49%)
		ATPase-Plipid	229..1247	CDD:273734	436/1090 (40%)
		E1-E2_ATPase	286..>371	CDD:278548	39/84 (46%)
		Cation_ATPase	645..741	CDD:289987	45/95 (47%)
		HAD_like	<942..1001	CDD:304363	37/58 (64%)
		PhoLip_ATPase_C	988..1240	CDD:292829	82/261 (31%)
XB994119	XP_002940236.3	P-type_ATPase_APLT_Dnf-like	36..980	CDD:319770	403/950 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010