DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18278 and ids

DIOPT Version :9

Sequence 1:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001073537.1	Gene:	ids / 559959	ZFINID:	ZDB-GENE-061215-37	Length:	561	Species:	Danio rerio

Alignment Length:	465	Identity:	94/465 - (20%)
Similarity:	165/465 - (35%)	Gaps:	140/465 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILVLACLGN---TASEKLPNILLILSDDQDVELRGMF--PM--EHTIEMLGFGGALFHNAYTPSP 66
            :.:...||.   .|..|..|:|.:::||....| |.:  |:  ...|:.|.....:|||||....
Zfish    13 VFIFHLLGRDVFAAKSKNFNVLYLIADDLRPTL-GCYSDPVVKSPNIDQLASLSVVFHNAYAQQA 76

  Fly    67 ICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWR-RALEPRALPYILQQHGYNTFFGGKYLNQY 130
            :|.|:|.|.||       ..|.::.....:..:|| .|.....||...:.:||.|...||..:..
Zfish    77 VCGPSRVSFLT-------SRRPDTTKLYDFNSYWRVHAGNYTTLPQYFKSNGYTTLSVGKVFHPG 134

  Fly   131 WGAG---DVPKGWNHFYGLHGNSRYY--NYTLRENSGNVHYESTYLTDLL--------------- 175
            ..:.   |.|..|: ....|..|..|  ....::..|.:|      ::||
Zfish   135 IASNHSDDYPYSWS-VPPYHPPSFEYEKRKVCKDKDGTLH------SNLLCPVNVSEMPLGTLPD 192

  Fly   176 ---RDRAADFLRNATQSSEPFFAMVA-----------------------------------PPAA 202
               .:.|...||:...|.:|||..|.                                   |..|
Zfish   193 MENTEEAIRLLRSMKGSQKPFFLSVGFYKPHIPFRIPQEYLKLYPIENMTLAPDPDVPKKLPDVA 257

  Fly   203 HEPFTPAPRHEGVFSHIEALRTP-SFNQVKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLAV 266
            :.|:|...:.|.|    :||... .:..:.:|....:|                 |..:.::..|
Zfish   258 YNPWTDIRKREDV----QALNLSFPYGPIPKDFQLRIR-----------------QHYFASVSYV 301

  Fly   267 DELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPLLIRGPGIA---- 327
            |..|..::..|:|....:||.::.:||:|:.:|:..: :.|...::....|||::...|::
Zfish   302 DAQVGKILQTLDDVGLAKNTIVVLSSDHGWSLGEHGE-WAKYSNFDVATRVPLMVYKAGVSSRRS 365

  Fly   328 ---------------PESH------IDTAVSLVDLAPTILAWADI------DTPSY-MD----GQ 360
                           ...|      :::.|.|:|:.||:...|.:      .:||: ||    |.
Zfish   366 RPGAKTFPFIDVFQDTREHFGKGKIVNSVVELLDVFPTLANLAGLPSVHHCPSPSFKMDLCTEGS 430

  Fly   361 SFHELLLNKR 370
            :...|:.|.:
Zfish   431 NLANLIRNPK 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	90/447 (20%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	90/447 (20%)
ids	NP_001073537.1	iduronate-2-sulfatase	29..527	CDD:293754	91/449 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810