DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18278 and Arsi

DIOPT Version :9

Sequence 1:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001033588.1	Gene:	Arsi / 545260	MGIID:	2670959	Length:	573	Species:	Mus musculus

Alignment Length:	382	Identity:	95/382 - (24%)
Similarity:	147/382 - (38%)	Gaps:	93/382 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NTASEKLPNILLILSDDQ---DVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTG 78
            :.|..:.|:|:.||:|||   ||...|......|::.|...|....|.|. .|||.|:|:.||||
Mouse    40 SVAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYI-QPICTPSRSQLLTG 103

  Fly    79 MYAHNHGTRNNSV---SGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVP--K 138
            .|..:.|.:::.:   ...|.      .|:...||..||:.||:|...||:...::....:|  :
Mouse   104 RYQIHTGLQHSIIRPRQPNCL------PLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRR 162

  Fly   139 GWNHFYG-LHGNSRYYNYTLRENSG----NVH--------YESTYLTDLLRDRAADFLRNATQSS 190
            |::.|.| |.||..||.|...:..|    ::|        ....|.|.|...||:..|.:....:
Mouse   163 GFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHNPQN 227

  Fly   191 EPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQDKHWLVRAARRLPNETINTIDTY 255
             |.|..||..|.|.|                |::|        :.:|.|         ..|:...
Mouse   228 -PLFLYVAFQAVHTP----------------LQSP--------REYLYR---------YRTMGNV 258

  Fly   256 FQKRWETLL-AVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPL 319
            .::::..:: .:||.|..:...|.......|:.||::||||            .|.:....|.||
Mouse   259 ARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG------------GQTFSGGSNWPL 311

  Fly   320 L----------IRGPGIAPESHID-------TAVSLVDLAPTILAWADIDTPSYMDG 359
            .          :||.|......:.       ..|.:.|..||::..|. .|.|..||
Mouse   312 RGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAG-GTTSAADG 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	94/375 (25%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	94/375 (25%)
Arsi	NP_001033588.1	AslA	47..492	CDD:225661	94/375 (25%)
		4-S	47..478	CDD:293753	94/375 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	515..550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740