Protein Alignment CG18278 and ARSD

DIOPT Version :9

• Sequence 1: NP_725289.1
• Gene: CG18278 / 36487
• FlyBaseID: FBgn0033836
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001660.2
• Gene: ARSD / 414
• HGNCID: 717
• Length: 593
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 132/635 - (20%)
• Similarity: 205/635 - (32%)
• Gaps: 224/635 - (35%)

  Fly     7 LIILVLACLGNTASEKLPNILLILSDDQDVELRGMF-------PMEHTIEMLGFGGALFHNAYTP 64
            |.:|:..|...||:...||||||::||......|.:       |   .|:.|...|.........
Human    24 LCLLLKTCEPKTANAFKPNILLIMADDLGTGDLGCYGNNTLRTP---NIDQLAEEGVRLTQHLAA 85

  Fly    65 SPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALP-------YILQQHGYNTFF 122
            :|:|.|:|.:.|||.::...|.   ..|.|.....|...  ...||       .|||||||.|..
Human    86 APLCTPSRAAFLTGRHSFRSGM---DASNGYRALQWNAG--SGGLPENETTFARILQQHGYATGL 145

  Fly   123 GGKYLNQYWGAG------------DVPKGWNHFYG------------------------LHGNSR 151
            .||     |..|            .:..|:::|||                        |.|.::
Human   146 IGK-----WHQGVNCASRGDHCHHPLNHGFDYFYGMPFTLTNDCDPGRPPEVDAALRAQLWGYTQ 205

  Fly   152 ----------------YYNYTLRENSGN-----VHYESTYLT-DLLRDRAADFLRNATQSSEPFF 194
                            :::.:.|..:|.     :.:.|.|.: ..:|......:||...:.:|
Human   206 FLALGILTLAAGQTCGFFSVSARAVTGMAGVGCLFFISWYSSFGFVRRWNCILMRNHDVTEQP-- 268

  Fly   195 AMVAPPAA----HEPFTPAPRHE-GVF--------SHIEALRTPSFNQVKQDKHWLVRAARRLPN 246
             ||....|    .|..:...||: |.|        .||..:.|.:|         |.::...|..
Human   269 -MVLEKTASLMLKEAVSYIERHKHGPFLLFLSLLHVHIPLVTTSAF---------LGKSQHGLYG 323

  Fly   247 ETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQ-- 309
            :.:..:|      |        |:..::..:.|.....:|:..:|||:|.|:       :.|.
Human   324 DNVEEMD------W--------LIGKVLNAIEDNGLKNSTFTYFTSDHGGHL-------EARDGH 367

  Fly   310 -----------------PYETDINVPLLIRGPGIAPESH-IDTAVSLVDLAPTI--LAWADIDTP 354
                             .:|..|.||.:...||:.|... |....||:|:.||:  |...::...
Human   368 SQLGGWNGIYKGGKGMGGWEGGIRVPGIFHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQD 432

  Fly   355 SYMDGQSFHELLLNKRRRVPFFERSLLIEYWGEGTLATFNPECPWPEKD-----RLAQCTPAADC 414
            ..:||.|...||.....|   .....|..|.|:...|     ..|.:||     ::...||  ..
Human   433 RVIDGHSLVPLLQGAEAR---SAHEFLFHYCGQHLHA-----ARWHQKDSGSVWKVHYTTP--QF 487

  Fly   415 HCQDAWNNTYACL-RNI---------RHREDRIYCEFRDNENFLEAYDLQLDPFQMTNIAYDLLP 469
            |.:.|.    ||. |.:         .||...:             :||..||.:...:..|..|
Human   488 HPEGAG----ACYGRGVCPCSGEGVTHHRPPLL-------------FDLSRDPSEARPLTPDSEP 535

  Fly   470 IERALYS-------------------LRLKN------LTQCSGH----SC 490
            :..|:.:                   ..:.|      |..|.||    ||
Human   536 LYHAVIARVGAAVSEHRQTLSPVPQQFSMSNILWKPWLQPCCGHFPFCSC 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	117/564 (21%)
		AslA	24..464	CDD:225661	117/561 (21%)
ARSD	NP_001660.2	ALP_like	40..563	CDD:304875	120/595 (20%)
		AslA	40..525	CDD:225661	117/557 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157169
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740