DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18278 and Arsi

DIOPT Version :9

Sequence 1:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001041346.1	Gene:	Arsi / 307404	RGDID:	1310242	Length:	573	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	97/383 - (25%)
Similarity:	149/383 - (38%)	Gaps:	95/383 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NTASEKLPNILLILSDDQ---DVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTG 78
            :.|..:.|:|:.||:|||   ||...|......|::.|...|....|.|. .|||.|:|:.||||
  Rat    40 SAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYI-QPICTPSRSQLLTG 103

  Fly    79 MYAHNHGTRNNSV---SGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVP--K 138
            .|..:.|.:::.:   ...|.      .|:...||..||:.||:|...||:...::....:|  :
  Rat   104 RYQIHTGLQHSIIRPRQPNCL------PLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRR 162

  Fly   139 GWNHFYG-LHGNSRYYNYTLRENSG----NVH--------YESTYLTDLLRDRAADFLRNATQS- 189
            |::.|.| |.||..||.|...:..|    ::|        ....|.|.|...||:..|  |:.|
  Rat   163 GFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHIL--ASHSP 225

  Fly   190 SEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQDKHWLVRAARRLPNETINTIDT 254
            .:|.|..||..|.|.|                |::|        :.:|.|         ..|:..
  Rat   226 QKPLFLYVAFQAVHTP----------------LQSP--------REYLYR---------YRTMGN 257

  Fly   255 YFQKRWETLL-AVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVP 318
            ..::::..:: .:||.|..:...|.......|:.||::||||            .|.:....|.|
  Rat   258 VARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG------------GQTFSGGSNWP 310

  Fly   319 LL----------IRGPGIAPESHID-------TAVSLVDLAPTILAWADIDTPSYMDG 359
            |.          :||.|......:.       ..|.:.|..||::..|. .|.|..||
  Rat   311 LRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAG-GTTSAADG 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	96/376 (26%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	96/376 (26%)
Arsi	NP_001041346.1	4-S	48..478	CDD:293753	95/375 (25%)
		AslA	49..485	CDD:225661	95/374 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	506..550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351109
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740