DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18278 and arsj

DIOPT Version :9

Sequence 1:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_002934299.2	Gene:	arsj / 100494972	XenbaseID:	XB-GENE-951842	Length:	564	Species:	Xenopus tropicalis

Alignment Length:	528	Identity:	113/528 - (21%)
Similarity:	199/528 - (37%)	Gaps:	142/528 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PNILLILSDDQ---DVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHG 85
            |:|:.||:|||   |:...|......|::.|...|....|.|. .|||.|:|:..:||.|..:.|
Frog    47 PHIVFILADDQGYRDIGYHGSEIRTPTLDKLASDGVRLENYYV-QPICSPSRSQFITGKYQIHTG 110

  Fly    86 TRNNSV---SGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVP--KGWNHFYG 145
            .:::.:   ...|.      .|:...||..|::.||.|...||:...::....:|  :|::.|:|
Frog   111 LQHSIIRPSQPNCL------PLDNMTLPQKLKKAGYQTHMVGKWHLGFYKKECMPTQRGFDSFFG 169

  Fly   146 -LHGNSRYYN-----------YTLRENSGNVHYE---STYLTDLLRDRAADFLRNATQSSEPFFA 195
             |.|:..|||           |.|.||: |..::   ..|.|::...|....| ::...::|.|.
Frog   170 SLLGSGDYYNHYKCDSPGICGYDLYENN-NAAWDQDNGIYSTEMYTQRVLQIL-SSHNPNKPLFL 232

  Fly   196 MVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQDKHWLVRAARRLPNETINTIDTYFQKRW 260
            .:|..|.|.|                |:.|.        ::|         :..|:|....::|:
Frog   233 YIAYQAVHSP----------------LQAPG--------NYL---------DNYNSILNENRRRY 264

  Fly   261 ETLLA-VDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPF----------DKRQPYETD 314
            ..:|: :|:.|..:...|......:|:.|||:||||      .||.          .|...:|..
Frog   265 AAMLSCLDDAVNNVTTALKKYGFYDNSIIIYSSDNG------GQPMAGGNNWPLRGSKGTYWEGG 323

  Fly   315 INVPLLIRGPGIAPESHI-DTAVSLVDLAPTI--LAWADIDTPSYMDGQSFHELLLNKRRRV--- 373
            |.....:..|.:..:.:| ...|.:.|..||:  ||..:||....:||....|.:...:|..
Frog   324 IRAVGFVHSPILKMKGYICKELVHITDWFPTLVTLAGGEIDEEIQLDGYDIWETISEGKRSPRQE 388

  Fly   374 ------PFF-------------------ERSLLIEYWGEGTLATFNPEC-PWPEKDRLAQCTPAA 412
                  |.:                   :.::.:.:|   .|.|.||.. .|......:...|
Frog   389 ILHNIDPMYTKARNGSWAAGYGIWNTAIQSAIRVNHW---KLLTGNPGYGDWIPPQSFSNVGP-- 448

  Fly   413 DCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFLEAYDLQLDPFQMTNIAYDLLP--IERALY 475
                 :.|:|....|.:.:.               :..:::..||::..::: |..|  :::.|.
Frog   449 -----NRWHNERVTLASGKS---------------VWLFNITADPYERIDLS-DRYPDIVKQLLR 492

  Fly   476 SLRLKNLT 483
            .|...|.|
Frog   493 RLAQFNKT 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	107/508 (21%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	107/505 (21%)
arsj	XP_002934299.2	4-S	47..480	CDD:293753	107/505 (21%)
arsj	XP_002934299.2	DUF4976	<466..>504	CDD:419068	8/36 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910