DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18278 and sulf1

DIOPT Version :9

Sequence 1:	NP_725289.1	Gene:	CG18278 / 36487	FlyBaseID:	FBgn0033836	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_012819608.1	Gene:	sulf1 / 100038259	XenbaseID:	XB-GENE-966419	Length:	1168	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	168/462 - (36%)
Similarity:	238/462 - (51%)	Gaps:	49/462 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ISLAPLIIL----VLACLGNTASEKL------------PNILLILSDDQDVELRGMFPMEHTIEM 50
            :|.|.:.||    :...||::...|.            |||:|:|:|||||||..:..|..|..:
Frog    46 LSFALVFILLQMEIPVGLGSSLKAKFRGRVQPDRRNIRPNIILVLTDDQDVELGSLQVMNKTRRI 110

  Fly    51 LGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQ 115
            :..|||.|.||:..:|:|||:|:|:|||.|.|||....|:.:  |..|.|:...|||.....|..
Frog   111 MEEGGASFINAFVTTPMCCPSRSSMLTGKYVHNHNIYTNNEN--CSSPSWQAIHEPRTFAVYLNN 173

  Fly   116 HGYNTFFGGKYLNQYWGAGDVPKGWNHFYGLHGNSRYYNYTL-----RENSGNVHYESTYLTDLL 175
            .||.|.|.|||||:|.|: .:|.||..:.||..|||:||||:     :|..| ..||..|.|||:
Frog   174 TGYRTAFFGKYLNEYNGS-YIPPGWREWLGLVKNSRFYNYTMCRNGFKEKHG-FEYEKDYFTDLI 236

  Fly   176 RDRAADF--LRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQV-KQDKHWL 237
            .:.:..:  |........|...:::..|.|.|...||:....|.:.....|||:|.. ..||||:
Frog   237 TNDSISYFKLSKKLYPHRPIMMVISHAAPHGPEDSAPQFSEFFPNASQHITPSYNYAPNMDKHWI 301

  Fly   238 VR-AARRLP--NETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVG 299
            :: ....||  .|..|.:   .:||.:|||:||:.:..|..:|.||..:||||:|||||:|||:|
Frog   302 MQYTGAMLPIHMEFTNVL---HRKRLQTLLSVDDSMEKLYNMLVDTGEVENTYLIYTSDHGYHIG 363

  Fly   300 QFAQPFDKRQPYETDINVPLLIRGPGIAPESHIDTAVSLVDLAPTILAWADIDTPSYMDGQSFHE 364
            ||.....|..||:.||.||..:|||.:.|.|.:...|..:|:|||||..|.:|||..|||:|...
Frog   364 QFGLVKGKSMPYDFDIRVPFFVRGPNVEPGSIVHQIVLNLDIAPTILDIAGLDTPPDMDGKSVLP 428

  Fly   365 LL----------LNKRRRVPFFERSLLIEYWGEGTLATFNPECPWPEKDRLAQCTPAADCHCQDA 419
            ||          .||:.::  :..:.|:|. |:.......|....|:.:.|.:.....:. ||.|
Frog   429 LLDIERPGNRLRTNKKNKI--WRDTFLVER-GKFLRKKEEPSKSSPQSNHLPKYERVKEL-CQQA 489

  Fly   420 WNNTYAC 426
            ...| ||
Frog   490 RYQT-AC 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18278	NP_725289.1	G6S	24..467	CDD:293766	161/424 (38%)
CG18278	NP_725289.1	AslA	24..464	CDD:225661	161/424 (38%)
sulf1	XP_012819608.1	G6S	83..425	CDD:293766	144/348 (41%)
		DUF3740	575..735	CDD:372181
		ALP_like	<823..872	CDD:390042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	1	1.000	-	-		FOG0001009
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920