Protein Alignment Dh31-R and adcyap1r1

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_031759329.1
• Gene: adcyap1r1 / 780260
• XenbaseID: XB-GENE-5805848
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 132/499 - (26%)
• Similarity: 206/499 - (41%)
• Gaps: 133/499 - (26%)

  Fly    60 PGAEAGTHCAGTFDGWLCWPDTAVGTSAYELCP------------DFI---TGFDP--------A 101
            ||      |.|.:|...||....||......||            ||:   .|:.|        |
 Frog    51 PG------CPGMWDNITCWMPAEVGKVVSIRCPALFSMLGSEDEMDFVDRSLGWAPENLEEQQSA 109

  Fly   102 RYAHKECGLDGEWFKHPLTNKTWSNYTTCVNLEDLN--------WRHTVNLISEVGYGTSLLAIL 158
            ....:.|..:| |..|      :.:|:...:. |:|        :..:|..:..|||.|||:|:.
 Frog   110 GIITRNCTENG-WTDH------FPHYSEACDF-DINETGPDQDTYYLSVKALYTVGYSTSLVALT 166

  Fly   159 LSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNSELL---------HQSPMRCV 214
            .::.||..|:.|.|.|..:|||||.||       ::..:.|....|:|         |.|.:.|.
 Frog   167 TAMVILCRFRKLHCTRNFIHMNLFVSF-------ILRAISVFIKDEVLYAEQDSNHCHLSTVECK 224

  Fly   215 ALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGG 279
            .:.:..||.::|||.|:..||.||.|:||..|..|:|...|....|||:|.|.:.::::.|
 Frog   225 VVMVFFHYCVMSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPLICVTIWAVLR---- 285

  Fly   280 TPEDNRHCWMNQTNYQN--ILMVPVCISMFLNLLFLCNIVRVVLLKLNAP------ASIQGSCGP 336
            ...|:..||....|:..  ::..||..|:.:|.:....|:.:::.||.:|      :||..||..
 Frog   286 LHFDDVGCWDMNDNFALWWVIKGPVIGSIMINFVLFVGIIIILVQKLQSPDIGGNESSIYFSCFQ 350

  Fly   337 -------------------SRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYE----II 378
                               |...|:..|:||||:||.|:.|.:..|.|      ||..:    :.
 Frog   351 KCFCKTKRANEHSFKMSELSIITLRLARSTLLLIPLFGIHYTVFAFSP------ENVSKRERLVF 409

  Fly   379 SAFTASFQGLCVAILFCFCNGEVIAQ--MKRKWRMMCFSNRPRTNSYTATQVSFVRCG----PPL 437
            .....||||..||||:||.|||.:.:  ::.|..|....::|           .:.||    |.:
 Frog   410 ELGLGSFQGFVVAILYCFLNGEFLPKGAIRNKEEMEELESQP-----------VLCCGFQTPPSV 463

  Fly   438 PGEEKVXLKDMSAKRRASAGPQHHQPHHQSHQLS-TDQQRARSQ 480
            .||::...:|.:.             |.:..||: :|.|..|.:
 Frog   464 SGEQRSERRDTTV-------------HSEQEQLTDSDVQHKRRE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	19/89 (21%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	95/313 (30%)
		TM helix 1	141..166	CDD:320388	10/24 (42%)
		TM helix 2	175..197	CDD:320388	7/21 (33%)
		TM helix 3	214..241	CDD:320388	10/26 (38%)
		TM helix 4	253..273	CDD:320388	6/19 (32%)
		TM helix 5	291..320	CDD:320388	6/30 (20%)
		TM helix 6	339..366	CDD:320388	11/26 (42%)
		TM helix 7	373..398	CDD:320388	11/28 (39%)
adcyap1r1	XP_031759329.1	HRM	50..135	CDD:397086	21/97 (22%)
		7tm_GPCRs	147..431	CDD:475119	92/300 (31%)
		TM helix 1	150..174	CDD:410628	10/23 (43%)
		TM helix 2	183..204	CDD:410628	8/27 (30%)
		TM helix 3	224..246	CDD:410628	7/21 (33%)
		TM helix 4	265..281	CDD:410628	6/15 (40%)
		TM helix 5	299..322	CDD:410628	5/22 (23%)
		TM helix 6	377..399	CDD:410628	11/27 (41%)
		TM helix 7	404..429	CDD:410628	10/24 (42%)