Protein Alignment Dh31-R and Crhr2

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001426277.1
• Gene: Crhr2 / 64680
• RGDID: 70547
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 125/444 - (28%)
• Similarity: 209/444 - (47%)
• Gaps: 89/444 - (20%)

  Fly    30 VAESG------PDFDALRAACE--TRLNASGQLAGSGGPGAEAGTHCAGTFDG-WLCWPDTAVGT 85
            ||:.|      |.:..|...|.  |..|.||..           ::|..|.|. ..|||.:|.|.
  Rat    25 VAQPGQALQDQPLWTLLEQYCHRTTTRNFSGPY-----------SYCNTTLDQIGTCWPQSAPGA 78

  Fly    86 SAYELCPDFITG--FDPARYAHKECGLDGEWFKHPLTNKTWS---NYTTCVNL-------EDLNW 138
            .....||::..|  ::..|.|::||          |.|.||:   ||:.|..:       .||::
  Rat    79 LVERPCPEYFNGIKYNTTRNAYREC----------LENGTWASRVNYSHCEPILDDKQRKYDLHY 133

  Fly   139 RHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLWLVWYLLVMPNS 203
            |..: :|:.:|:..|::|::.:..:....:|::|.|..:|.||..:|...|   :.|:||.:.:.
  Rat   134 RIAL-IINYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRN---ITWFLLQLIDH 194

  Fly   204 ELLHQSPMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVKWLIAF-GWGSPAIV 267
            |:...:.:.|..:....:||:::|:.||..||.||||.:|..: |.:.|.|||..| ||..|..:
  Rat   195 EVHEGNEVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTY-STEHLRKWLFLFIGWCIPCPI 258

  Fly   268 IFVYSMARGLGGTPEDNRHCWMNQ-----TNYQNILMVPVCISMFLNLLFLCNIVRVVLLKLNAP 327
            |    :|..:|....:|..||..:     .:|  |...|:.:.:.:|.:||.||||:::.||.|.
  Rat   259 I----VAWAVGKLYYENEQCWFGKEPGDLVDY--IYQGPIILVLLINFVFLFNIVRILMTKLRAS 317

  Fly   328 ASIQGSCGPSRTV--LQAFRATLLLVPLLGLQYILTPFRPAPKHPWENTYEIISAFTASFQGLCV 390
            .:       |.|:  .:|.:|||:|:||||:.|:|....|......:..:...::|..||||..|
  Rat   318 TT-------SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFV 375

  Fly   391 AILFCFCNGEVIAQMKRKW--------------RMMCFSNRPRTNSYTATQVSF 430
            ::.:||.||||.:.::::|              |.|.....|       |::||
  Rat   376 SVFYCFFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSP-------TRISF 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	22/72 (31%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	85/293 (29%)
		TM helix 1	141..166	CDD:320388	4/24 (17%)
		TM helix 2	175..197	CDD:320388	6/21 (29%)
		TM helix 3	214..241	CDD:320388	10/26 (38%)
		TM helix 4	253..273	CDD:320388	8/20 (40%)
		TM helix 5	291..320	CDD:320388	10/33 (30%)
		TM helix 6	339..366	CDD:320388	12/28 (43%)
		TM helix 7	373..398	CDD:320388	8/24 (33%)
Crhr2	NP_001426277.1	None