Protein Alignment Dh31-R and Pth1r

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_038937952.2
• Gene: Pth1r / 56813
• RGDID: 3442
• Length: 709
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 151/511 - (29%)
• Similarity: 238/511 - (46%)
• Gaps: 78/511 - (15%)

  Fly    65 GTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTT 129
            |..|...:|..:|||..|.|......|||:|..|:...:|::.|..:|.|...|..|:||:||:.
  Rat   223 GRPCLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSE 287

  Fly   130 CVNLEDLNWRH-----TVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASF---A 186
            |:.......|.     .:.:|..|||..||.::.:::.||.||:.|.|.|..:||::|.||   |
  Rat   288 CLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRA 352

  Fly   187 ANNSLWL---VWYL-LVMPNSELLHQSPMRCVA-----------------LHITLH-YFLLSNYS 229
            |  |:::   |.|. ..:..:|.|.:..:..:|                 :.:|.. |||.:||.
  Rat   353 A--SIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYY 415

  Fly   230 WMLCEGFYLHTVLVAAFISEKRLVKWLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMNQTNY 294
            |:|.||.|||:::..||.|||:.:.....||||.||:.:.|:...|....    |..||...:.:
  Rat   416 WILVEGLYLHSLIFMAFFSEKKYLWGFTIFGWGLPAVFVAVWVGVRATLA----NTGCWDLSSGH 476

  Fly   295 QN-ILMVPVCISMFLNLLFLCNIVRVVLLKL---NAPASIQGSCGPSRTVLQAFRATLLLVPLLG 355
            :. |:.||:..|:.||.:...||:||:..||   ||     |.|...:...:..|:||:||||.|
  Rat   477 KKWIIQVPILASVVLNFILFINIIRVLATKLRETNA-----GRCDTRQQYRKLLRSTLVLVPLFG 536

  Fly   356 LQY---ILTPFRPAPKHPW--ENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKWR----M 411
            :.|   :..|:.......|  :..||::  |. ||||..|||::|||||||.|::::.|.    .
  Rat   537 VHYTVFMALPYTEVSGTLWQIQMHYEML--FN-SFQGFFVAIIYCFCNGEVQAEIRKSWSRWTLA 598

  Fly   412 MCFSNRPRTNS--------YTATQVSFV--RCGPPLPGEEKVXLKDMSAKRRASAGPQHHQPHHQ 466
            :.|..:.|:.|        .:.|.|:.|  |.|..||...::   ..:.....|..|.|.:|...
  Rat   599 LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLSLPLSPRL---PPATTNGHSQLPGHAKPGAP 660

  Fly   467 SHQLSTDQQRARSQSLASSSSFLEGWRDRMPFLKRRQTIDHSRQSQPLMEEGGETV 522
            :.:..|   ...:.::.....||.|....:.     :....|.:..||::|..|||
  Rat   661 ATETET---LPVTMAVPKDDGFLNGSCSGLD-----EEASGSARPPPLLQEEWETV 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	24/66 (36%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	102/314 (32%)
		TM helix 1	141..166	CDD:320388	8/24 (33%)
		TM helix 2	175..197	CDD:320388	9/27 (33%)
		TM helix 3	214..241	CDD:320388	14/44 (32%)
		TM helix 4	253..273	CDD:320388	7/19 (37%)
		TM helix 5	291..320	CDD:320388	9/29 (31%)
		TM helix 6	339..366	CDD:320388	10/29 (34%)
		TM helix 7	373..398	CDD:320388	12/24 (50%)
Pth1r	XP_038937952.2	None