Protein Alignment Dh31-R and crhr1

DIOPT Version :10

• Sequence 1: NP_001260951.1
• Gene: Dh31-R / 36475
• FlyBaseID: FBgn0052843
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_696346.3
• Gene: crhr1 / 567940
• ZFINID: ZDB-GENE-081231-1
• Length: 430
• Species: Danio rerio
• Alignment Length: 398
• Identity: 116/398 - (29%)
• Similarity: 191/398 - (47%)
• Gaps: 64/398 - (16%)

  Fly    65 GTHCAGTFDG-WLCWPDTAVGTSAYELCPDFITG--FDPARYAHKECGLDGEWFKHPLTNKTWSN 126
            |..|..:.|| ..|||.::.|......||:...|  ::.....::||..:|.|.|.       .|
Zfish    56 GLFCNTSIDGIGTCWPRSSAGEVVSRPCPESFLGVRYNTTNNVYRECLANGTWAKK-------GN 113

  Fly   127 YTTCVNL------EDLNWRHTVNLISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASF 185
            |:.|..:      ..|:: |...:|:.:|:..||.|:|::..:....:|::|.|..:|.||..:|
Zfish   114 YSQCQEILNEEKKSKLHY-HIAVIINYLGHCISLGALLVAFILFMRLRSIRCLRNIIHWNLITAF 177

  Fly   186 AANNSLWLVWYLLVMPNSELLHQS-PMRCVALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISE 249
            ...|:.|.|..|.:.|.   :|:| .:.|..:....:||.::|:.||..||.||||.:|..:.::
Zfish   178 ILRNATWFVVQLTMNPE---VHESNVIWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTD 239

  Fly   250 KRLVKWL-IAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWMNQ-----TNYQNILMVPVCISMFL 308
            | |.||: |..||..|..:|    :|..:|....||..||..:     |:|  |...|:.:.:.:
Zfish   240 K-LRKWMFICIGWCIPFPII----VAWAIGKLYYDNEKCWFGKRAGIYTDY--IYQGPMILVLLI 297

  Fly   309 NLLFLCNIVRVVLLKLNAPASIQGSCGPSRTV--LQAFRATLLLVPLLGLQYILTPFRPAPKHPW 371
            |.:||.||||:::.||.|..:       |.|:  .:|.:|||:|:||||:.|:|....|......
Zfish   298 NFIFLFNIVRILMTKLRASTT-------SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEIS 355

  Fly   372 ENTYEIISAFTASFQGLCVAILFCFCNGEVIAQMKRKW--------------RMMCFSNRPRTNS 422
            :..:...::|..||||..|::.:||.|.||.:.::::|              |.|.....|
Zfish   356 QIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSP---- 416

  Fly   423 YTATQVSF 430
               |:|||
Zfish   417 ---TRVSF 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:397086	19/69 (28%)
		7tmB1_NPR_B4_insect-like	139..411	CDD:320388	89/294 (30%)
		TM helix 1	141..166	CDD:320388	6/24 (25%)
		TM helix 2	175..197	CDD:320388	7/21 (33%)
		TM helix 3	214..241	CDD:320388	10/26 (38%)
		TM helix 4	253..273	CDD:320388	7/20 (35%)
		TM helix 5	291..320	CDD:320388	11/33 (33%)
		TM helix 6	339..366	CDD:320388	12/28 (43%)
		TM helix 7	373..398	CDD:320388	8/24 (33%)
crhr1	XP_696346.3	HormR	55..126	CDD:214468	19/76 (25%)
		7tmB1_CRF-R1	131..395	CDD:320561	89/281 (32%)
		TM helix 1	133..158	CDD:320561	6/24 (25%)
		TM helix 2	167..189	CDD:320561	7/21 (33%)
		TM helix 3	204..230	CDD:320561	9/25 (36%)
		TM helix 4	243..263	CDD:320561	8/23 (35%)
		TM helix 5	280..309	CDD:320561	11/30 (37%)
		TM helix 6	323..350	CDD:320561	11/26 (42%)
		TM helix 7	357..382	CDD:320561	8/24 (33%)