DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dh31-R and calcrlb

DIOPT Version :9

Sequence 1:	NP_001260951.1	Gene:	Dh31-R / 36475	FlyBaseID:	FBgn0052843	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_001920035.3	Gene:	calcrlb / 567131	ZFINID:	ZDB-GENE-080924-1	Length:	466	Species:	Danio rerio

Alignment Length:	386	Identity:	151/386 - (39%)
Similarity:	223/386 - (57%)	Gaps:	33/386 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 GTHCAGTFDGWLCWPDTAVGTSAYELCPDFITGFDPARYAHKECGLDGEWFKHPLTNKTWSNYTT 129
            |:.|..|:||||||.....|.::.:.||::...||.:..|.|.|...|.||.||.:|:||||||.
Zfish    67 GSMCKRTWDGWLCWEYMEPGVTSAQHCPNYFDDFDTSEVATKICTNSGHWFVHPESNRTWSNYTD 131

  Fly   130 CVNLEDLNWRHTVNL--ISEVGYGTSLLAILLSLAILGYFKSLKCARITLHMNLFASFAANNSLW 192
            |....:.:.:..:||  ::.:|:|.||:::..||.|..|||||.|.|||||.|||.||..|:.:.
Zfish   132 CRLKSNDHKKTALNLYYLTLIGHGLSLISLFTSLGIFFYFKSLSCQRITLHKNLFFSFVLNSVIT 196

  Fly   193 LVWYLLVMPNSELLHQSPMRC---VALHITLHYFLLSNYSWMLCEGFYLHTVLVAAFISEKRLVK 254
            ::::..|..|.|:...:|:.|   |.:|   ||.|..||.||||||.||||::|.|..:||:.:.
Zfish   197 IIFFTCVANNQEVTEANPVSCKVSVFIH---HYLLGCNYFWMLCEGIYLHTLIVVAVFAEKQHLM 258

  Fly   255 WLIAFGWGSPAIVIFVYSMARGLGGTPEDNRHCWM-NQTNYQNILMVPVCISMFLNLLFLCNIVR 318
            |....|||.|.|..|:::::|..    ..|.:||: :.|:...|:..|:|.::.:||.||.||||
Zfish   259 WYYLLGWGFPLIPAFIHAISRSY----YYNDNCWISSNTSLLYIIHGPICAALLVNLFFLLNIVR 319

  Fly   319 VVLLKLNAPASIQGSCGPSRTVLQAFRATLLLVPLLGLQYILTPFRPAPKHPWE---NTYEIISA 380
            |::.||......:.|     ..::|.||||:||||||:||:|.|::|..:...|   :|..|:
Zfish   320 VLITKLKVTHQAESS-----VYMRAVRATLILVPLLGIQYLLLPYKPDGRLASEIFIHTTNIL-- 377

  Fly   381 FTASFQGLCVAILFCFCNGEVIAQMKRKWRMM------CFSNRP-RTNSYTATQVSFV-RC 433
              ..:|||.||.:|||.|.||...::|.|...      .|:|.. |:.||||:.::.| ||
Zfish   378 --MHYQGLLVATIFCFFNSEVQGVLRRHWNQYRTQFGGTFANTALRSASYTASSMTEVHRC 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dh31-R	NP_001260951.1	HRM	65..132	CDD:280888	30/66 (45%)
Dh31-R	NP_001260951.1	7tm_4	140..390	CDD:304433	101/258 (39%)
calcrlb	XP_001920035.3	HRM	67..132	CDD:280888	29/64 (45%)
calcrlb	XP_001920035.3	7tm_2	143..385	CDD:278432	101/257 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3304
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21179
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2818
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1005634at2759
OrthoFinder	1	1.000	-	-		FOG0001436
OrthoInspector	1	1.000	-	-		mtm6498
orthoMCL	1	0.900	-	-		OOG6_105420
Panther	1	1.100	-	-	O	PTHR45620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.970